Reactome | Interaction of Tie2 with Ang1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10468134
displayName	Interaction of Tie2 with Ang1
eventOf	[Pathway:R-SSC-210993] Tie2 Signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-210881] Dimerization of Tie2/Ang1 complex - Sus scrofa
inferredFrom	[Reaction:R-HSA-204779] Interaction of Tie2 with Ang1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-204854] ANGPT1 [extracellular region] [EntityWithAccessionedSequence:R-SSC-197755] TEK [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of Tie2 with Ang1
output	[Complex:R-SSC-204807] ANGPT1:TEK [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-204779
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-210993] Tie2 Signaling
(precedingEvent)	[Reaction:R-SSC-210881] Dimerization of Tie2/Ang1 complex
(inferredTo)	[Reaction:R-HSA-204779] Interaction of Tie2 with Ang1

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