YAP1 binds TEAD1

Stable Identifier
R-HSA-2032775
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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YAP1 binds TEAD1
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In the nucleus the YAP1 transcriptional coactivator can bind any one of the four TEAD transcription factors to form a complex. The stoichiometry of this complex is unknown (Chan et al. 2009).

Literature References
PubMed ID Title Journal Year
19324876 TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

Lim, CJ, Hong, W, Loo, LS, Huang, C, Chan, SW, Chong, YF

J Biol Chem 2009
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Orthologous Events
YAP1 binds TEAD1 (Bos taurus)
YAP1 binds TEAD1 (Caenorhabditis elegans)
YAP1 binds TEAD1 (Danio rerio)
YAP1 binds TEAD1 (Drosophila melanogaster)
YAP1 binds TEAD1 (Gallus gallus)
YAP1 binds TEAD1 (Mus musculus)
YAP1 binds TEAD1 (Rattus norvegicus)
YAP1 binds TEAD1 (Sus scrofa)
YAP1 binds TEAD1 (Xenopus tropicalis)
Authored
D'Eustachio, P  (2012-02-03)
Reviewed
Sudol, M  (2012-02-03)
Created
D'Eustachio, P  (2012-01-07)
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