Reactome | Association of profilin with monomeric actin

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Association of profilin with monomeric actin Show undefined attributes

authored	[InstanceEdit:201902] Pollard, T, 2007-09-30 10:07:47
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:203078] Matthews, L, 2007-11-12 14:35:15
dbId	203070
displayName	Association of profilin with monomeric actin
edited	[InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
eventOf	[Pathway:R-HSA-5663220] RHO GTPases Activate Formins - Homo sapiens
followingEvent	[Reaction:R-HSA-5665659] RAC1:GTP:FMNL1 binds profilin:G-actin - Homo sapiens
input	[Complex:R-HSA-201857] G-actin [cytosol] [CandidateSet:R-HSA-203077] PFN [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5665665] Profilin-actin complexes directly elongate actin filaments at the barbed end [LiteratureReference:5665671] The role of profilin in actin polymerization and nucleotide exchange [LiteratureReference:203082] X-ray structure determination of human profilin II: A comparative structural analysis of human profilins
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Association of profilin with monomeric actin
orthologousEvent	[Reaction:R-GGA-203070] Association of profilin with monomeric actin - Gallus gallus [Reaction:R-XTR-203070] Association of profilin with monomeric actin - Xenopus tropicalis [Reaction:R-DRE-203070] Association of profilin with monomeric actin - Danio rerio [Reaction:R-SSC-203070] Association of profilin with monomeric actin - Sus scrofa [Reaction:R-BTA-203070] Association of profilin with monomeric actin - Bos taurus [Reaction:R-CFA-203070] Association of profilin with monomeric actin - Canis familiaris [Reaction:R-RNO-203070] Association of profilin with monomeric actin - Rattus norvegicus [Reaction:R-MMU-203070] Association of profilin with monomeric actin - Mus musculus
output	[Complex:R-HSA-203080] Profilin:G-actin [cytosol]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-203070
summation	[Summation:5665672] Profilins PFN1 and PFN2 bind to monomeric actin (G-actin), f...

Referrals

(hasEvent)	[Pathway:R-HSA-5663220] RHO GTPases Activate Formins
(precedingEvent)	[Reaction:R-HSA-5665659] RAC1:GTP:FMNL1 binds profilin:G-actin