Reactome | Caspase mediated cleavage of C-IAP1

Schema > Reaction > Entries

Caspase mediated cleavage of C-IAP1 Show undefined attributes

authored	[InstanceEdit:201620] Schulze-Osthoff, K, 2007-09-03 07:52:18
catalystActivity	[CatalystActivity:114327] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:202961] Matthews, L, 2007-11-12 10:29:28
dbId	202960
displayName	Caspase mediated cleavage of C-IAP1
edited	[InstanceEdit:201989] Matthews, L, 2007-10-09 13:44:38 [InstanceEdit:202801] Matthews, L, 2007-11-11 23:40:56
eventOf	[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-50847] BIRC2 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:202958] c-IAP1 is cleaved by caspases to produce a proapoptotic C-terminal fragment
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Caspase mediated cleavage of C-IAP1
orthologousEvent	[Reaction:R-DME-202960] Caspase mediated cleavage of C-IAP1 - Drosophila melanogaster [Reaction:R-GGA-202960] Caspase mediated cleavage of C-IAP1 - Gallus gallus [Reaction:R-XTR-202960] Caspase mediated cleavage of C-IAP1 - Xenopus tropicalis [Reaction:R-DRE-202960] Caspase mediated cleavage of C-IAP1 - Danio rerio [Reaction:R-SSC-202960] Caspase mediated cleavage of C-IAP1 - Sus scrofa [Reaction:R-BTA-202960] Caspase mediated cleavage of C-IAP1 - Bos taurus [Reaction:R-CFA-202960] Caspase mediated cleavage of C-IAP1 - Canis familiaris [Reaction:R-RNO-202960] Caspase mediated cleavage of C-IAP1 - Rattus norvegicus [Reaction:R-MMU-202960] Caspase mediated cleavage of C-IAP1 - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-202913] BIRC2(1-372) [cytosol] [EntityWithAccessionedSequence:R-HSA-202931] BIRC2(373-618) [cytosol]
precedingEvent	[Reaction:R-HSA-114252] Cleavage of Procaspase-3 by the apoptosome - Homo sapiens [Reaction:R-HSA-114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - Homo sapiens [Reaction:R-HSA-418845] Activation of caspase-3 - Homo sapiens
releaseDate	2006-01-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:204051] Ranganathan, S, 2007-11-23 00:10:26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-202960
summation	[Summation:202963] c-IAP1 is cleaved by caspase-3 producing a proapoptotic C-te...

Referrals

(hasEvent)

[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins