Reactome | Recruitment of PLCgamma to membrane

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Recruitment of PLCgamma to membrane Show undefined attributes

authored	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:2029269] Garapati, P V, 2012-01-04
dbId	2029270
displayName	Recruitment of PLCgamma to membrane
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
eventOf	[Pathway:R-HSA-2029485] Role of phospholipids in phagocytosis - Homo sapiens
followingEvent	[Reaction:R-HSA-2029268] Phosphorylation and activation of PLCG - Homo sapiens
input	[Complex:R-HSA-2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] [DefinedSet:R-HSA-1169089] PLC gamma1,2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2028806] Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk [LiteratureReference:2028992] Tyrosine phosphorylation of phospholipase C-gamma 2 is involved in the activation of phosphoinositide hydrolysis by Fc receptors in human neutrophils
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Recruitment of PLCgamma to membrane
orthologousEvent	[Reaction:R-GGA-2029270] Recruitment of PLCgamma to membrane - Gallus gallus [Reaction:R-SSC-2029270] Recruitment of PLCgamma to membrane - Sus scrofa [Reaction:R-BTA-2029270] Recruitment of PLCgamma to membrane - Bos taurus [Reaction:R-CFA-2029270] Recruitment of PLCgamma to membrane - Canis familiaris [Reaction:R-RNO-2029270] Recruitment of PLCgamma to membrane - Rattus norvegicus [Reaction:R-MMU-2029270] Recruitment of PLCgamma to membrane - Mus musculus
output	[Complex:R-HSA-2029137] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane]
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2029270
summation	[Summation:2028868] PLCgamma (PLCG) is recruited to FCGR and the phosphorylated ...

Referrals

(hasEvent)	[Pathway:R-HSA-2029485] Role of phospholipids in phagocytosis
(precedingEvent)	[Reaction:R-HSA-2029268] Phosphorylation and activation of PLCG