Reactome | ERKs are inactivated

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ERKs are inactivated Show undefined attributes

created	[InstanceEdit:202683] Jassal, Bijay, 2007-11-08
crossReference	[DatabaseIdentifier:12819513] BioModels Database:BIOMD0000000251 [DatabaseIdentifier:12819465] BioModels Database:BIOMD0000000255 [DatabaseIdentifier:12819433] BioModels Database:BIOMD0000000653 [DatabaseIdentifier:12819435] BioModels Database:BIOMD0000000656 [DatabaseIdentifier:12819505] BioModels Database:BIOMD0000000557 [DatabaseIdentifier:12819437] BioModels Database:BIOMD0000000648 [DatabaseIdentifier:12819471] BioModels Database:BIOMD0000000175 [DatabaseIdentifier:12819441] BioModels Database:BIOMD0000000655 [DatabaseIdentifier:12819443] BioModels Database:BIOMD0000000652 [DatabaseIdentifier:12819445] BioModels Database:BIOMD0000000654
dbId	202670
displayName	ERKs are inactivated
eventOf	[Pathway:R-HSA-198753] ERK/MAPK targets - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-199959] ERKs are inactivated by protein phosphatase 2A - Homo sapiens [Reaction:R-HSA-203797] ERKs are inactivated by dual-specific phosphatases (DUSPs) - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2016-12-21
literatureReference	[LiteratureReference:202673] Structure and regulation of MAPK phosphatases [LiteratureReference:202675] A module of negative feedback regulators defines growth factor signaling
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	ERKs are inactivated
orthologousEvent	[Pathway:R-SCE-202670] ERKs are inactivated - Saccharomyces cerevisiae [Pathway:R-SPO-202670] ERKs are inactivated - Schizosaccharomyces pombe [Pathway:R-DDI-202670] ERKs are inactivated - Dictyostelium discoideum [Pathway:R-CEL-202670] ERKs are inactivated - Caenorhabditis elegans [Pathway:R-DME-202670] ERKs are inactivated - Drosophila melanogaster [Pathway:R-GGA-202670] ERKs are inactivated - Gallus gallus [Pathway:R-XTR-202670] ERKs are inactivated - Xenopus tropicalis [Pathway:R-DRE-202670] ERKs are inactivated - Danio rerio [Pathway:R-SSC-202670] ERKs are inactivated - Sus scrofa [Pathway:R-BTA-202670] ERKs are inactivated - Bos taurus [Pathway:R-CFA-202670] ERKs are inactivated - Canis familiaris [Pathway:R-RNO-202670] ERKs are inactivated - Rattus norvegicus [Pathway:R-MMU-202670] ERKs are inactivated - Mus musculus
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-202670
summation	[Summation:202679] MAP Kinases are inactivated by a family of protein named MAP...
updateTrackers	[UpdateTracker:9787038] Update Tracker - [Pathway:202670] ERKs are inactivated - v46:[updateContainedRLE] [UpdateTracker:9782619] Update Tracker - [Pathway:202670] ERKs are inactivated - v59:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9787038] Update Tracker - [Pathway:202670] ERKs are inactivated - v46:[updateContainedRLE] [UpdateTracker:9782619] Update Tracker - [Pathway:202670] ERKs are inactivated - v59:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-198753] ERK/MAPK targets

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