Reactome | p-S177,S181-IKBKB [cytosol]

catalystActivities	[CatalystActivity:208866] protein serine/threonine kinase activity of p-S177,S181-IKBKB [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-193888] Phospho-IKK-beta homdimer [cytosol] - Homo sapiens [Complex:R-HSA-193888] Phospho-IKK-beta homdimer [cytosol] - Homo sapiens [Complex:R-HSA-202562] CHUK:p-S177,S181-IKBKB:pUb-IKBKG [cytosol] - Homo sapiens [Complex:R-HSA-727820] Active IKK complex [cytosol] - Homo sapiens
created	[InstanceEdit:202512] Garapati, P V, 2007-10-31 11:22:38
dbId	202506
deleted	[Deleted:205147] Deletion of instance: 193954
displayName	p-S177,S181-IKBKB [cytosol]
endCoordinate	756
hasModifiedResidue	[ModifiedResidue:193958] O-phospho-L-serine at 177 [ModifiedResidue:193953] O-phospho-L-serine at 181
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-202506] phospho-p-S177,S181-IKBKB [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-202506] phospho-p-S177,S181-IKBKB [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-202506] phospho-IKBKB [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-202506] phospho-p-S177,S181-IKBKB [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-202506] phospho-IKBKB [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-202506] phospho-ikbkb [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-202506] phospho-ikbkb [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-202506] phospho-p-S177,S181-IKBKB [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-202506] phospho-p-S177,S181-IKBKB [cytosol] - Drosophila melanogaster
maxDepth	1
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	p-S177,S181-IKBKB Phospho-IKK2 IKK-beta IKKB Inhibitor of nuclear factor kappa B kinase beta subunit
referenceEntity	[ReferenceGeneProduct:uniprot:O14920] UniProt:O14920 IKBKB
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-202506
startCoordinate	1
updateTrackers	[UpdateTracker:9879267] Update Tracker - [EntityWithAccessionedSequence:202506] p-S177,S181-IKBKB [cytosol] - v44:[modifyName] [UpdateTracker:9870867] Update Tracker - [EntityWithAccessionedSequence:202506] p-S177,S181-IKBKB [cytosol] - v38:[modifyName]

(updatedInstance)	[UpdateTracker:9879267] Update Tracker - [EntityWithAccessionedSequence:202506] p-S177,S181-IKBKB [cytosol] - v44:[modifyName] [UpdateTracker:9870867] Update Tracker - [EntityWithAccessionedSequence:202506] p-S177,S181-IKBKB [cytosol] - v38:[modifyName]
(replacementInstances)	[Deleted:205147] Deletion of instance: 193954
(hasComponent)	[Complex:R-HSA-727820] Active IKK complex [cytosol] [Complex:R-HSA-193888] Phospho-IKK-beta homdimer [cytosol] [Complex:R-HSA-202562] CHUK:p-S177,S181-IKBKB:pUb-IKBKG [cytosol] [Complex:R-HSA-177663] IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] [Complex:R-HSA-202513] CHUK:p-S177,S181-IKBKB:IKBKG [cytosol]
(activeUnit)	[CatalystActivity:202546] protein serine/threonine kinase activity of CHUK:p-S177,S181-IKBKB:pUb-IKBKG [cytosol] [CatalystActivity:9773806] protein serine/threonine kinase activity of CHUK:p-S177,S181-IKBKB:IKBKG [cytosol] [CatalystActivity:450351] protein serine/threonine kinase activity of IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] [CatalystActivity:9773797] IkappaB kinase activity of CHUK:p-S177,S181-IKBKB:IKBKG [cytosol]
(physicalEntity)	[CatalystActivity:208866] protein serine/threonine kinase activity of p-S177,S181-IKBKB [cytosol]

p-S177,S181-IKBKB [cytosol] Show undefined attributes

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