Reactome | p-2S-SMAD1/5/8:SMAD4 [nucleoplasm]

Schema > Complex > Entries

p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-201427] p-2S-SMAD1/5/8:SMAD4:SKI [nucleoplasm] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-201425] Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling - Homo sapiens [Reaction:R-HSA-201423] SKI complexes with the Smad complex, suppressing BMP2 signalling - Homo sapiens
created	[InstanceEdit:201460] Jassal, B, 2007-08-13 08:42:05
dbId	201450
displayName	p-2S-SMAD1/5/8:SMAD4 [nucleoplasm]
hasComponent	2 × [DefinedSet:R-HSA-201444] Phospho-R-SMAD1/5/9 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-177103] SMAD4 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Mus musculus [Complex:R-RNO-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Canis familiaris [Complex:R-BTA-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Bos taurus [Complex:R-SSC-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Sus scrofa [Complex:R-XTR-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Gallus gallus [Complex:R-DME-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - Caenorhabditis elegans
maxDepth	3
modified	[InstanceEdit:8877932] Orlic-Milacic, Marija, 2016-06-28
name	p-2S-SMAD1/5/8:SMAD4 Phospho-r-SMAD1/5/8:Co-SMAD complex
producedByEvent	[Reaction:R-HSA-201472] The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-201450
updateTrackers	[UpdateTracker:9870828] Update Tracker - [Complex:201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - v38:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9870828] Update Tracker - [Complex:201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] - v38:[addName]
(input)	[BlackBoxEvent:R-HSA-201425] Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling [Reaction:R-HSA-201423] SKI complexes with the Smad complex, suppressing BMP2 signalling
(hasComponent)	[Complex:R-HSA-201427] p-2S-SMAD1/5/8:SMAD4:SKI [nucleoplasm]
(output)	[Reaction:R-HSA-201472] The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus

© 2026 Reactome

Cite Us!