Reactome | SMAD4 [nucleoplasm]

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SMAD4 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-206654] p-2S-SMAD1:p-2S-SMAD1:SMAD4 [nucleoplasm] - Homo sapiens [Complex:R-HSA-8878153] p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm] - Homo sapiens
created	[InstanceEdit:177100] Jassal, B, 2006-03-22 11:41:32
dbId	177103
displayName	SMAD4 [nucleoplasm]
endCoordinate	552
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-177103] SMAD4 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-177103] SMAD4 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-177103] SMAD4 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-177103] SMAD4 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-177103] SMAD4 [nucleoplasm] - Sus scrofa [GenomeEncodedEntity:R-DRE-177103] Ghost homologue of SMAD4 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-177103] smad4 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-177103] LOC121108244 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-177103-2] SMAD4 [nucleoplasm] - Gallus gallus [DefinedSet:R-GGA-177103-3] Homologues of SMAD4 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-177103] Med [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-177103] SMAD4 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-177103-2] daf-3 [nucleoplasm] - Caenorhabditis elegans [DefinedSet:R-CEL-177103-3] Homologues of SMAD4 [nucleoplasm] - Caenorhabditis elegans
maxDepth	1
modified	[InstanceEdit:2167891] Orlic-Milacic, M, 2012-03-22
name	SMAD4 Co-SMAD Mothers against decapentaplegic homolog 4
producedByEvent	[Reaction:R-HSA-209055] PPM1A dephosphorylates nuclear SMAD2/3 - Homo sapiens [Reaction:R-HSA-209055] PPM1A dephosphorylates nuclear SMAD2/3 - Homo sapiens [Reaction:R-HSA-209055] PPM1A dephosphorylates nuclear SMAD2/3 - Homo sapiens [Reaction:R-HSA-2179276] SMURF2 monoubiquitinates SMAD3 - Homo sapiens [Reaction:R-HSA-2179276] SMURF2 monoubiquitinates SMAD3 - Homo sapiens [Reaction:R-HSA-2179276] SMURF2 monoubiquitinates SMAD3 - Homo sapiens [Reaction:R-HSA-9737710] SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q13485] UniProt:Q13485 SMAD4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-177103
startCoordinate	1
updateTrackers	[UpdateTracker:9866529] Update Tracker - [EntityWithAccessionedSequence:177103] SMAD4 [nucleoplasm] - v23:[modifyName] [UpdateTracker:9872736] Update Tracker - [EntityWithAccessionedSequence:177103] SMAD4 [nucleoplasm] - v41:[modifyEndCoordinate] [UpdateTracker:9870529] Update Tracker - [EntityWithAccessionedSequence:177103] SMAD4 [nucleoplasm] - v38:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9866529] Update Tracker - [EntityWithAccessionedSequence:177103] SMAD4 [nucleoplasm] - v23:[modifyName] [UpdateTracker:9872736] Update Tracker - [EntityWithAccessionedSequence:177103] SMAD4 [nucleoplasm] - v41:[modifyEndCoordinate] [UpdateTracker:9870529] Update Tracker - [EntityWithAccessionedSequence:177103] SMAD4 [nucleoplasm] - v38:[addName]
(output)	[Reaction:R-HSA-9737710] SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter [Reaction:R-HSA-209055] PPM1A dephosphorylates nuclear SMAD2/3 [Reaction:R-HSA-2179276] SMURF2 monoubiquitinates SMAD3
(hasComponent)	[Complex:R-HSA-206654] p-2S-SMAD1:p-2S-SMAD1:SMAD4 [nucleoplasm] [Complex:R-HSA-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] [Complex:R-HSA-9736939] p-T,2S-SMAD3:p-T,2S-SMAD3:SMAD4 [nucleoplasm] [Complex:R-HSA-9736938] p-T,2S-SMAD2:p-T,2S-SMAD3:SMAD4 [nucleoplasm] [Complex:R-HSA-9736936] p-T,2S-SMAD2:p-T,2S-SMAD2:SMAD4 [nucleoplasm] [Complex:R-HSA-8878153] p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm] [Complex:R-HSA-9736929] p-2S-SMAD2:p-2S-SMAD3:SMAD4 [nucleoplasm] [Complex:R-HSA-206827] p-2S-SMAD2:p-2S-SMAD2:SMAD4 [nucleoplasm]

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