Reactome | SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix

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SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix Show undefined attributes

authored	[InstanceEdit:199189] D'Eustachio, P, 2007-07-09 22:03:12
catalystActivity	[CatalystActivity:199228] coenzyme A transmembrane transporter activity of SLC25A16 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:199189] D'Eustachio, P, 2007-07-09 22:03:12
dbId	199216
displayName	SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix
eventOf	[Pathway:R-HSA-199220] Vitamin B5 (pantothenate) metabolism - Homo sapiens
input	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:199239] Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine [LiteratureReference:199196] The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix [LiteratureReference:9837329] Regulation of coenzyme A levels by degradation: the 'Ins and Outs'
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix CoA(out) <=> CoA(in)
orthologousEvent	[Reaction:R-SCE-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Saccharomyces cerevisiae [Reaction:R-SPO-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Schizosaccharomyces pombe [Reaction:R-DDI-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Dictyostelium discoideum [Reaction:R-GGA-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Gallus gallus [Reaction:R-XTR-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Xenopus tropicalis [Reaction:R-DRE-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Danio rerio [Reaction:R-SSC-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Sus scrofa [Reaction:R-BTA-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Bos taurus [Reaction:R-CFA-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Canis familiaris [Reaction:R-RNO-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Rattus norvegicus [Reaction:R-MMU-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Mus musculus
output	[SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-196773] COASY phosphorylates DP-CoA - Homo sapiens
releaseDate	2006-08-02
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-199216
summation	[Summation:199184] Graves disease carrier protein (SLC25A16), associated with t...
updateTrackers	[UpdateTracker:9787958] Update Tracker - [Reaction:199216] SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix - v44:[modifyText] [UpdateTracker:9842293] Update Tracker - [Reaction:199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - v86:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9787958] Update Tracker - [Reaction:199216] SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix - v44:[modifyText] [UpdateTracker:9842293] Update Tracker - [Reaction:199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - v86:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-199220] Vitamin B5 (pantothenate) metabolism

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