Reactome | p-S166,S188-MDM2 [cytosol]

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p-S166,S188-MDM2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-6793666] MDM2 translocates to the nucleus - Homo sapiens
created	[InstanceEdit:198616] Jassal, B, 2007-06-29 07:57:48
dbId	198638
displayName	p-S166,S188-MDM2 [cytosol]
endCoordinate	491
hasModifiedResidue	[ModifiedResidue:2399939] O-phospho-L-serine at 166 [ModifiedResidue:2399935] O-phospho-L-serine at 188
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-198638] phospho-Mdm2 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-198638] phospho-Mdm2 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-198638] phospho-MDM2 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-198638] phospho-MDM2 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-198638] phospho-MDM2 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-198638] phospho-mdm2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-198638] phospho-mdm2 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-198638-2] phospho-mdm2 [cytosol] - Xenopus tropicalis [DefinedSet:R-XTR-198638-3] Homologues of p-S166,S188-MDM2 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-198638] phospho-MDM2 [cytosol] - Gallus gallus
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	p-S166,S188-MDM2 p-S166,188-MDM2 p-MDM2 Phospho-MDM2
producedByEvent	[BlackBoxEvent:R-HSA-9851102] NPM1-ALK- and PI3K-dependent MDM2 phosphorylation - Homo sapiens [Reaction:R-HSA-2399981] AKT1 E17K mutant phosphorylates MDM2 - Homo sapiens [Reaction:R-HSA-198599] AKT phosphorylates MDM2 - Homo sapiens [Reaction:R-HSA-6795460] SGK1 phosphorylates MDM2 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:95018] UniProt:Q00987 MDM2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-198638
startCoordinate	1

Referrals

(output)	[BlackBoxEvent:R-HSA-9851102] NPM1-ALK- and PI3K-dependent MDM2 phosphorylation [Reaction:R-HSA-2399981] AKT1 E17K mutant phosphorylates MDM2 [Reaction:R-HSA-198599] AKT phosphorylates MDM2 [Reaction:R-HSA-6795460] SGK1 phosphorylates MDM2
(input)	[Reaction:R-HSA-6793666] MDM2 translocates to the nucleus

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