Reactome | NOTCH1 binds DLL/JAG ligand in cis

Schema > Reaction > Entries

authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1980137] Orlic-Milacic, M, 2011-11-08
dbId	1980138
displayName	NOTCH1 binds DLL/JAG ligand in cis
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
eventOf	[Pathway:R-HSA-2122948] Activated NOTCH1 Transmits Signal to the Nucleus - Homo sapiens
inferredFrom	[Reaction:R-NUL-2076711] rDll1 binds NOTCH1 in cis - Homo sapiens [Reaction:R-DME-2076706] Serrate binds Notch in cis - Drosophila melanogaster
input	[DefinedSet:R-HSA-157643] DLL/JAG [plasma membrane] [Complex:R-HSA-157027] NOTCH1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9911644] Orlic-Milacic, Marija, 2024-06-03
name	NOTCH1 binds DLL/JAG ligand in cis
output	[Complex:R-HSA-1980055] NOTCH1:DLL/JAG [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-1912382] Mature NOTCH heterodimer traffics to the plasma membrane - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1980138
summation	[Summation:2077244] Binding of NOTCH1 to DLL/JAG ligands expressed in the same c...
updateTrackers	[UpdateTracker:9919370] Update Tracker - [Reaction:1980138] NOTCH1 binds DLL/JAG ligand in cis - v90:[addLiteratureReference, modifyText]

(updatedInstance)	[UpdateTracker:9919370] Update Tracker - [Reaction:1980138] NOTCH1 binds DLL/JAG ligand in cis - v90:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-2122948] Activated NOTCH1 Transmits Signal to the Nucleus
(inferredTo)	[Reaction:R-DME-2076706] Serrate binds Notch in cis [Reaction:R-NUL-2076711] rDll1 binds NOTCH1 in cis

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