Reduction of desmosterol to cholesterol

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9643615] delta24-sterol reductase activity of DHCR24 [endoplasmic reticulum membrane] Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis
category transition
compartment
created [InstanceEdit:196422] D'Eustachio, P, 2007-04-21 18:35:08
crossReference
dbId 196417
displayName Reduction of desmosterol to cholesterol
edited
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isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name
  • Reduction of desmosterol to cholesterol
  • desmosterol + NADPH + H(+) => cholesterol + NADP(+)
orthologousEvent
output
precedingEvent
releaseDate 2007-02-20
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-196417
summation
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