Reactome | Androgen biosynthesis

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Androgen biosynthesis Show undefined attributes

authored	[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
created	[InstanceEdit:193053] Jassal, B, 2007-02-13 10:16:33
dbId	193048
displayName	Androgen biosynthesis
edited	[InstanceEdit:196368] Jassal, B, 2007-04-20 21:09:56
eventOf	[Pathway:R-HSA-196071] Metabolism of steroid hormones - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:21391] androgen biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-193068] CYP17A1 17-hydroxylates PREG - Homo sapiens [Reaction:R-HSA-193070] CYP17A1 cleaves 17aHPREG to DHA - Homo sapiens [Reaction:R-HSA-193073] HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST - Homo sapiens [Reaction:R-HSA-193072] CYP17A1 17-hydroxylates P4 to 17aHPROG - Homo sapiens [Reaction:R-HSA-193099] CYP17A1 cleaves 17aHPROG to ANDST - Homo sapiens [Reaction:R-HSA-193064] HSD17B3-like proteins reducde ANDST to TEST - Homo sapiens [Reaction:R-HSA-469659] SRD5A1 dehydrogenates TEST to DHTEST - Homo sapiens [Reaction:R-HSA-9705713] SRD5A2 dehydrogenates TEST to DHTEST - Homo sapiens [Reaction:R-HSA-9705794] SRD5A2 binds SRD5A2 inhibitors - Homo sapiens [Reaction:R-HSA-9705714] SRD5A3 dehydrogenates TEST to DHTEST - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-06-09
literatureReference	[LiteratureReference:1449535] Disorders of androgen biosynthesis
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Androgen biosynthesis
orthologousEvent	[Pathway:R-PFA-193048] Androgen biosynthesis - Plasmodium falciparum [Pathway:R-SCE-193048] Androgen biosynthesis - Saccharomyces cerevisiae [Pathway:R-SPO-193048] Androgen biosynthesis - Schizosaccharomyces pombe [Pathway:R-DDI-193048] Androgen biosynthesis - Dictyostelium discoideum [Pathway:R-CEL-193048] Androgen biosynthesis - Caenorhabditis elegans [Pathway:R-DME-193048] Androgen biosynthesis - Drosophila melanogaster [Pathway:R-GGA-193048] Androgen biosynthesis - Gallus gallus [Pathway:R-XTR-193048] Androgen biosynthesis - Xenopus tropicalis [Pathway:R-DRE-193048] Androgen biosynthesis - Danio rerio [Pathway:R-SSC-193048] Androgen biosynthesis - Sus scrofa [Pathway:R-BTA-193048] Androgen biosynthesis - Bos taurus [Pathway:R-CFA-193048] Androgen biosynthesis - Canis familiaris [Pathway:R-RNO-193048] Androgen biosynthesis - Rattus norvegicus [Pathway:R-MMU-193048] Androgen biosynthesis - Mus musculus
releaseDate	2007-05-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:196370] D'Eustachio, P, 2007-04-20 21:11:21
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-193048
summation	[Summation:193056] Androgens are the determining factors for male development a...
updateTrackers	[UpdateTracker:9776611] Update Tracker - [Pathway:193048] Androgen biosynthesis - v75:[addHasEvent, updateContainedRLE] [UpdateTracker:9786092] Update Tracker - [Pathway:193048] Androgen biosynthesis - v50:[updateContainedRLE] [UpdateTracker:9774754] Update Tracker - [Pathway:193048] Androgen biosynthesis - v81:[addHasEvent] [UpdateTracker:9788925] Update Tracker - [Pathway:193048] Androgen biosynthesis - v39:[updateContainedRLE] [UpdateTracker:9790478] Update Tracker - [Pathway:193048] Androgen biosynthesis - v33:[addHasEvent] [UpdateTracker:9775766] Update Tracker - [Pathway:193048] Androgen biosynthesis - v78:[updateContainedRLE] [UpdateTracker:9789282] Update Tracker - [Pathway:193048] Androgen biosynthesis - v38:[addLiteratureReference, modifyText, updateContainedRLE]

Referrals

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[Pathway:R-HSA-196071] Metabolism of steroid hormones

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