Reactome | Sialylation of Pre-NOTCH

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Sialylation of Pre-NOTCH Show undefined attributes

authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
catalystActivity	[CatalystActivity:1499958] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL3/4/6 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:1912377] Orlic-Milacic, M, 2011-11-01
dbId	1912378
displayName	Sialylation of Pre-NOTCH
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
eventOf	[Pathway:R-HSA-1912420] Pre-NOTCH Processing in Golgi - Homo sapiens
followingEvent	[Reaction:R-HSA-1912372] Fringe-modified Pre-NOTCH is cleaved by FURIN - Homo sapiens
inferredFrom	[Reaction:R-CGR-2033005] Sialylation of Pre-Notch - Cricetulus griseus
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [CandidateSet:R-HSA-1911423] Glc,Gal-GlcNAc-Fuc-Pre-NOTCH [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:208198] Fringe is a glycosyltransferase that modifies Notch [LiteratureReference:1022100] The human sialyltransferase family
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Sialylation of Pre-NOTCH
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [CandidateSet:R-HSA-1911509] Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH [Golgi membrane]
precedingEvent	[Reaction:R-HSA-1912352] Galactosylation of Pre-NOTCH - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1912378
summation	[Summation:2033010] Mature fringe-modified NOTCH usually has a tetrasaccharide a...
updateTrackers	[UpdateTracker:9788698] Update Tracker - [Reaction:1912378] Sialylation of Pre-NOTCH - v41:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9788698] Update Tracker - [Reaction:1912378] Sialylation of Pre-NOTCH - v41:[modifyText]
(hasEvent)	[Pathway:R-HSA-1912420] Pre-NOTCH Processing in Golgi
(precedingEvent)	[Reaction:R-HSA-1912372] Fringe-modified Pre-NOTCH is cleaved by FURIN
(inferredTo)	[Reaction:R-CGR-2033005] Sialylation of Pre-Notch

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