Reactome | MIR150 microRNA binds 3'UTR of NOTCH3 mRNA

Schema > Reaction > Entries

authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1912361] Orlic-Milacic, M, 2011-11-01
dbId	1912362
displayName	MIR150 microRNA binds 3'UTR of NOTCH3 mRNA
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2121209] May, B, 2012-02-09 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06 [InstanceEdit:1609686] Jupe, S, 2011-09-27 [InstanceEdit:2121211] Gillespie, ME, 2012-02-09
eventOf	[Pathway:R-HSA-1912408] Pre-NOTCH Transcription and Translation - Homo sapiens
input	[DefinedSet:R-HSA-1852612] miR-150 RISC [cytosol] [EntityWithAccessionedSequence:R-HSA-1911478] NOTCH3 mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1892027] Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MIR150 microRNA binds 3'UTR of NOTCH3 mRNA
output	[Complex:R-HSA-1911497] NOTCH3 mRNA:miR-150 RISC [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-1912415] NOTCH3 gene transcription - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1912362
summation	[Summation:1852630] Translation of NOTCH3 mRNA is inhibited by miR-150 microRNA ...

(hasEvent)

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