MIR150 microRNA binds 3'UTR of NOTCH3 mRNA

Stable Identifier
R-HSA-1912362
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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MIR150 microRNA binds 3'UTR of NOTCH3 mRNA
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Translation of NOTCH3 mRNA is inhibited by miR-150 microRNA which binds to the 3'UTR of NOTCH3 mRNA. miR-150 is involved in regulation of differentiation of B-cells and T-cells.
Literature References
PubMed ID Title Journal Year
21551231 Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150

Bronte, V, Indraccolo, S, Basso, G, Gerosa, G, D'Agostino, DM, Amadori, A, Mussolin, L, Guffanti, A, Basso, K, De Bellis, G, Stellin, G, Ruggero, K, Ghisi, M, Frasson, C, Zanovello, P, Mukherjee, S, Corradin, A, Bonanno, L, Serafin, V

Blood 2011
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Authored
Orlic-Milacic, M  (2011-11-14)
Egan, SE  (2011-11-14)
Reviewed
Haw, R  (2012-02-06)
Created
Orlic-Milacic, M  (2011-11-02)
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