Reactome | FGFR1 ligand binding and activation

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648482
displayName	FGFR1 ligand binding and activation
eventOf	[Pathway:R-DRE-5654736] Signaling by FGFR1 - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24611] fibroblast growth factor receptor signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-DRE-190370] FGFR1b ligand binding and activation - Danio rerio [Pathway:R-DRE-190373] FGFR1c ligand binding and activation - Danio rerio [Pathway:R-DRE-190374] FGFR1c and Klotho ligand binding and activation - Danio rerio
inferredFrom	[Pathway:R-HSA-190242] FGFR1 ligand binding and activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	FGFR1 ligand binding and activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-190242
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5654736] Signaling by FGFR1
(inferredTo)	[Pathway:R-HSA-190242] FGFR1 ligand binding and activation

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