Reactome | FGF2(143-288) [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

FGF2(143-288) [extracellular region] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-5654351] FGFRL1-binding FGFs [extracellular region] - Homo sapiens
compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-9839344] FGF2:TGFBR3 [plasma membrane] - Homo sapiens [Complex:R-HSA-2684512] SDC1,2,4,(3):FGF2 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-2684507] Syndecans 1, 2, 4, (3) bind FGF2 - Homo sapiens [Reaction:R-HSA-9839379] TGFBR3 binding to FGF2 - Homo sapiens
created	[InstanceEdit:189861] de Bono, B, 2006-12-08 10:55:09
dbId	189898
displayName	FGF2(143-288) [extracellular region]
endCoordinate	288
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-189898] FGF2(143-288) [extracellular region] - Mus musculus [EntityWithAccessionedSequence:R-RNO-189898] FGF2(143-288) [extracellular region] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-189898] FGF2(143-288) [extracellular region] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-189898] FGF2(143-288) [extracellular region] - Bos taurus [EntityWithAccessionedSequence:R-SSC-189898] FGF2 [extracellular region] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-189898] fgf2 [extracellular region] - Danio rerio [EntityWithAccessionedSequence:R-XTR-189898] fgf2 [extracellular region] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-189898] FGF2(143-288) [extracellular region] - Gallus gallus [EntityWithAccessionedSequence:R-CEL-189898] let-756 [extracellular region] - Caenorhabditis elegans
maxDepth	1
memberOf	[DefinedSet:R-HSA-2426289] FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] - Homo sapiens [DefinedSet:R-HSA-8851713] FGF1,2 [extracellular region] - Homo sapiens [DefinedSet:R-HSA-6790034] STAT3-upregulated extracellular proteins [extracellular region] - Homo sapiens
modified	[InstanceEdit:9967508] D'Eustachio, Peter, 2025-09-29
name	FGF2(143-288) FGF2 Fibroblast growth factor-2 Heparin-binding growth factor 2 FGF2_HUMAN Basic fibroblast growth factor bFGF
positivelyRegulates	[PositiveRegulation:9757507] Positive regulation by 'FGF2(10-155) [extracellular region]' [PositiveGeneExpressionRegulation:9774491] Positive gene expression regulation by 'FGF2(10-155) [extracellular region]'
producedByEvent	[BlackBoxEvent:R-HSA-480515] Expression of FGF2 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P09038] UniProt:P09038 FGF2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-189898
startCoordinate	143
updateTrackers	[UpdateTracker:9876410] Update Tracker - [EntityWithAccessionedSequence:189898] FGF2(10-155) [extracellular region] - v44:[addName] [UpdateTracker:9884510] Update Tracker - [EntityWithAccessionedSequence:189898] FGF2(10-155) [extracellular region] - v45:[addName] [UpdateTracker:9972339] Update Tracker - [EntityWithAccessionedSequence:189898] FGF2(143-288) [extracellular region] - v95:[modifyEndCoordinate, modifyName, modifyStartCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9876410] Update Tracker - [EntityWithAccessionedSequence:189898] FGF2(10-155) [extracellular region] - v44:[addName] [UpdateTracker:9884510] Update Tracker - [EntityWithAccessionedSequence:189898] FGF2(10-155) [extracellular region] - v45:[addName] [UpdateTracker:9972339] Update Tracker - [EntityWithAccessionedSequence:189898] FGF2(143-288) [extracellular region] - v95:[modifyEndCoordinate, modifyName, modifyStartCoordinate]
(input)	[Reaction:R-HSA-9839379] TGFBR3 binding to FGF2 [Reaction:R-HSA-2684507] Syndecans 1, 2, 4, (3) bind FGF2
(hasMember)	[DefinedSet:R-HSA-6790034] STAT3-upregulated extracellular proteins [extracellular region] [DefinedSet:R-HSA-2426289] FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] [DefinedSet:R-HSA-8851713] FGF1,2 [extracellular region] [DefinedSet:R-HSA-2065925] FGFR2b mutant-binding FGFs [extracellular region] [DefinedSet:R-HSA-5656048] FGF2,7,10,22 [extracellular region] [DefinedSet:R-HSA-189959] FGFR4-binding FGFs [extracellular region] [DefinedSet:R-HSA-189963] FGFR1b-binding FGFs [extracellular region] [DefinedSet:R-HSA-189953] FGFR1c-binding FGFs [extracellular region] [DefinedSet:R-HSA-189957] FGFR2c-binding FGFs [extracellular region] [DefinedSet:R-HSA-189955] FGFR3c-binding FGFs [extracellular region]
(hasComponent)	[Complex:R-HSA-2684512] SDC1,2,4,(3):FGF2 [plasma membrane] [Complex:R-HSA-9839344] FGF2:TGFBR3 [plasma membrane]
(regulator)	[PositiveRegulation:9757507] Positive regulation by 'FGF2(10-155) [extracellular region]' [PositiveGeneExpressionRegulation:9774491] Positive gene expression regulation by 'FGF2(10-155) [extracellular region]'
(hasCandidate)	[CandidateSet:R-HSA-5654351] FGFRL1-binding FGFs [extracellular region]
(output)	[BlackBoxEvent:R-HSA-480515] Expression of FGF2

Cite Us!