Reactome | TGFBR3 binding to FGF2

Schema > Reaction > Entries

TGFBR3 binding to FGF2 Show undefined attributes

authored	[InstanceEdit:9840908] Tiwari, Krishna, 2023-07-25
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9839369] Tiwari, Krishna, 2023-07-05
dbId	9839379
displayName	TGFBR3 binding to FGF2
edited	[InstanceEdit:9840908] Tiwari, Krishna, 2023-07-25
eventOf	[Pathway:R-HSA-9839397] TGFBR3 regulates FGF2 signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-9839381] FGF2:TGFBR3 binding to GIPC1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-189898] FGF2(143-288) [extracellular region] [EntityWithAccessionedSequence:R-HSA-9839336] TGFBR3_mem [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9840155] Binding of two growth factor families to separate domains of the proteoglycan betaglycan [LiteratureReference:9840062] Type III TGF-? receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	TGFBR3 binding to FGF2
orthologousEvent	[Reaction:R-GGA-9839379] TGFBR3 binding to FGF2 - Gallus gallus [Reaction:R-XTR-9839379] TGFBR3 binding to FGF2 - Xenopus tropicalis [Reaction:R-DRE-9839379] TGFBR3 binding to FGF2 - Danio rerio [Reaction:R-SSC-9839379] TGFBR3 binding to FGF2 - Sus scrofa [Reaction:R-BTA-9839379] TGFBR3 binding to FGF2 - Bos taurus [Reaction:R-CFA-9839379] TGFBR3 binding to FGF2 - Canis familiaris [Reaction:R-RNO-9839379] TGFBR3 binding to FGF2 - Rattus norvegicus [Reaction:R-MMU-9839379] TGFBR3 binding to FGF2 - Mus musculus
output	[Complex:R-HSA-9839344] FGF2:TGFBR3 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-9839388] TGFBR3 translocation to plasma membrane - Homo sapiens
releaseDate	2024-06-15
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9839379
summation	[Summation:9840115] TGFBR3 (Betaglycan) bind bFGF via its heparan sulphate chain...

Referrals

(hasEvent)	[Pathway:R-HSA-9839397] TGFBR3 regulates FGF2 signaling
(precedingEvent)	[Reaction:R-HSA-9839381] FGF2:TGFBR3 binding to GIPC1