Reactome | C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane]

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C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] Show undefined attributes

compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:188131] de Bono, B, 2006-09-30 14:23:12
dbId	188132
displayName	C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane]
hasComponent	[Complex:R-HSA-1679575] C-ter TLR7 dimer [endosome membrane] [DefinedSet:R-NUL-9684904] TLR7, TLR8 ligands [endosome lumen]
inDisease	false
includedLocation	[Compartment:171907] endosome lumen
literatureReference	[LiteratureReference:1679106] Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains [LiteratureReference:2428797] Comparative analysis of species-specific ligand recognition in Toll-like receptor 8 signaling: a hypothesis [LiteratureReference:188159] Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 [LiteratureReference:188144] Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
maxDepth	4
memberOf	[DefinedSet:R-HSA-975158] Activated TLR7-9 homodimers [endosome membrane] - Homo sapiens
modified	[InstanceEdit:9767582] Shamovsky, Veronica, 2022-02-28
name	C-ter TLR7 dimer:TLR7, TLR8 ligands
producedByEvent	[Reaction:R-HSA-167983] C-ter TLR7 dimer binds TLR7, TLR8 ligands - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus [Species:164493] Human immunodeficiency virus 1 [Species:9031716] Influenza A virus [Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-188132
updateTrackers	[UpdateTracker:9903233] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9871215] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9870599] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v38:[modifyName] [UpdateTracker:9901448] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v74:[add_removeHasComponent, modifyName, updateContainedComponent] [UpdateTracker:9870035] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9901291] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v73:[add_removeHasComponent] [UpdateTracker:9869820] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v35:[add_removeCompartment] [UpdateTracker:9872909] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v42:[addLiteratureReference] [UpdateTracker:9902825] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9867342] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v25:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9903233] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9871215] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9870599] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v38:[modifyName] [UpdateTracker:9901448] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v74:[add_removeHasComponent, modifyName, updateContainedComponent] [UpdateTracker:9870035] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9901291] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v73:[add_removeHasComponent] [UpdateTracker:9869820] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v35:[add_removeCompartment] [UpdateTracker:9872909] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v42:[addLiteratureReference] [UpdateTracker:9902825] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9867342] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v25:[updateContainedComponent]
(output)	[Reaction:R-HSA-167983] C-ter TLR7 dimer binds TLR7, TLR8 ligands
(hasMember)	[DefinedSet:R-HSA-975158] Activated TLR7-9 homodimers [endosome membrane]

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