C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane]

Stable Identifier
R-HSA-188132
Type
Complex
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1, Influenza A virus, Human SARS coronavirus, Severe acute respiratory syndrome coronavirus 2
Compartment
endosome membrane
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
12032557 Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Jurk, M, Heil, F, Vollmer, J, Schetter, C, Krieg, AM, Wagner, H, Lipford, G, Bauer, S

Nat Immunol 2002
19521997 Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains

Wei, T, Gong, J, Jamitzky, F, Heckl, WM, Stark, RW, Rössle, SC

Protein Sci 2009
21949866 Comparative analysis of species-specific ligand recognition in Toll-like receptor 8 signaling: a hypothesis

Govindaraj, RG, Manavalan, B, Basith, S, Choi, S

PLoS ONE 2011
14976262 Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Heil, F, Hemmi, H, Hochrein, H, Ampenberger, F, Kirschning, C, Akira, S, Lipford, G, Wagner, H, Bauer, S

Science 2004
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