Reactome | I(1,3,4,5,6)P5 transports from the ER lumen to the nucleus

Schema > BlackBoxEvent > Entries

I(1,3,4,5,6)P5 transports from the ER lumen to the nucleus Show undefined attributes

authored	[InstanceEdit:1855226] Williams, MG, 2011-10-28
category	omitted
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:7660] nucleoplasm
created	[InstanceEdit:1855226] Williams, MG, 2011-10-28
dbId	1855160
displayName	I(1,3,4,5,6)P5 transports from the ER lumen to the nucleus
edited	[InstanceEdit:1855226] Williams, MG, 2011-10-28
eventOf	[Pathway:R-HSA-1855156] IPs transport between ER lumen and nucleus - Homo sapiens
followingEvent	[Reaction:R-HSA-1855181] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus - Homo sapiens [Reaction:R-HSA-1855176] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus - Homo sapiens [Reaction:R-HSA-1855161] I(1,3,4,5,6)P5 transports from the nucleus to the cytosol - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:160101] nuclear transport
input	[SimpleEntity:R-ALL-2024008] I(1,3,4,5,6)P5 [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1889807] The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase [LiteratureReference:1889938] Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase [LiteratureReference:1889802] Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress
maxDepth	1
modified	[InstanceEdit:9954157] D'Eustachio, Peter, 2025-06-06
name	I(1,3,4,5,6)P5 transports from the ER lumen to the nucleus
output	[SimpleEntity:R-ALL-2023901] I(1,3,4,5,6)P5 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-1855195] I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen - Homo sapiens [Reaction:R-HSA-1855225] IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen - Homo sapiens
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-1855160
summation	[Summation:2024003] Inositol 1,3,4,5,6-pentakisphosphate (I(1,3,4,5,6)P5) transl...

Referrals

(hasEvent)	[Pathway:R-HSA-1855156] IPs transport between ER lumen and nucleus
(precedingEvent)	[Reaction:R-HSA-1855181] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus [Reaction:R-HSA-1855176] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus [Reaction:R-HSA-1855161] I(1,3,4,5,6)P5 transports from the nucleus to the cytosol

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