I(1,3,4,5,6)P5 transports from the ER lumen to the nucleus

Stable Identifier
R-HSA-1855160
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Inositol 1,3,4,5,6-pentakisphosphate (I(1,3,4,5,6)P5) translocates from the endoplasmic reticulum (ER) lumen to the nucleus (Verbsky et al. 2002, Brehm et al. 2007, Choi et al. 2007).

Literature References
PubMed ID Title Journal Year
17702752 Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress

Choi, JH, Williams, J, Cho, J, Falck, JR, Shears, SB

J Biol Chem 2007
17705785 Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase

Brehm, MA, Schenk, TM, Zhou, X, Fanick, W, Lin, H, Windhorst, S, Nalaskowski, MM, Kobras, M, Shears, SB, Mayr, GW

Biochem J 2007
12084730 The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase

Verbsky, JW, Wilson, MP, Kisseleva, MV, Majerus, PW, Wente, SR

J Biol Chem 2002
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