Reactome | Association of XRCC4:DNA ligase IV complex with viral DNA ends

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Association of XRCC4:DNA ligase IV complex with viral DNA ends Show undefined attributes

authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	175177
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Association of XRCC4:DNA ligase IV complex with viral DNA ends
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
eventOf	[Pathway:R-HSA-164843] 2-LTR circle formation - Homo sapiens
followingEvent	[Reaction:R-HSA-175258] 2-LTR formation due to circularization of viral DNA - Homo sapiens
input	[Complex:R-HSA-175247] Ku proteins bound to viral DNA [nucleoplasm] [Complex:R-HSA-75912] XRCC4:LIG4 [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[Book:175927] 9780879695712 Integration Retroviruses Coffin, JM
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of XRCC4:DNA ligase IV complex with viral DNA ends
output	[Complex:R-HSA-175440] viral DNA:Ku proteins:XRCC4:DNA ligase IV complex [nucleoplasm]
precedingEvent	[Reaction:R-HSA-175174] Association of Ku heterodimer with viral DNA ends - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-175177
summation	[Summation:180399] XRCC4 and DNA ligase 4 are recruited to the complex containi...

Referrals

(hasEvent)	[Pathway:R-HSA-164843] 2-LTR circle formation
(precedingEvent)	[Reaction:R-HSA-175258] 2-LTR formation due to circularization of viral DNA

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