Reactome | C7 binds C5b:C6

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C7 binds C5b:C6 Show undefined attributes

authored	[InstanceEdit:114498] de Bono, B, 2004-08-04 09:17:50
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:173710] de Bono, B, 2006-02-16 11:51:13
dbId	173709
displayName	C7 binds C5b:C6
eventOf	[Pathway:R-HSA-166665] Terminal pathway of complement - Homo sapiens
followingEvent	[Reaction:R-HSA-2530453] Vitronectin (VTN) binds to C5b:C6:C7 - Homo sapiens [Reaction:R-HSA-173720] C5b:C6:C7 translocates to the plasma membrane - Homo sapiens
input	[Complex:R-HSA-173711] C5b:C6 [extracellular region] [EntityWithAccessionedSequence:R-HSA-173707] C7 [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:173730] Molecular organization and function of the complement system
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	C7 binds C5b:C6
orthologousEvent	[Reaction:R-GGA-2132133] C5b:C6:C7 inserts into the target cell membrane - Gallus gallus [Reaction:R-GGA-2132060] Formation of C5b:C6:C7 - Gallus gallus [Reaction:R-GGA-173709] C7 binds C5b:C6 - Gallus gallus [Reaction:R-XTR-173709] C7 binds C5b:C6 - Xenopus tropicalis [Reaction:R-SSC-173709] C7 binds C5b:C6 - Sus scrofa [Reaction:R-BTA-173709] C7 binds C5b:C6 - Bos taurus [Reaction:R-CFA-173709] C7 binds C5b:C6 - Canis familiaris [Reaction:R-MMU-173709] C7 binds C5b:C6 - Mus musculus
output	[Complex:R-HSA-173708] C5b:C6:C7 [extracellular region]
precedingEvent	[Reaction:R-HSA-173705] C5b binds C6 - Homo sapiens
regulatedBy	[NegativeRegulation:R-HSA-8852768] Negative regulation by 'CLU:C5b:C6:C7, C8, C9 [extracellular region]'
releaseDate	2006-08-02
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:181939] D'Eustachio, P, 2006-07-03 21:35:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-173709
summation	[Summation:8979564] The C5b:C6 complex binds C7. Normally the C5b:C6 complex rem...
updateTrackers	[UpdateTracker:9781852] Update Tracker - [Reaction:173709] C7 binds C5b:C6 - v60:[addSummation] [UpdateTracker:9783667] Update Tracker - [Reaction:173709] C7 binds C5b:C6 - v56:[addRegulator]

Referrals

(updatedInstance)	[UpdateTracker:9781852] Update Tracker - [Reaction:173709] C7 binds C5b:C6 - v60:[addSummation] [UpdateTracker:9783667] Update Tracker - [Reaction:173709] C7 binds C5b:C6 - v56:[addRegulator]
(hasEvent)	[Pathway:R-HSA-166665] Terminal pathway of complement
(precedingEvent)	[Reaction:R-HSA-2530453] Vitronectin (VTN) binds to C5b:C6:C7 [Reaction:R-HSA-173720] C5b:C6:C7 translocates to the plasma membrane