Reactome | C5b:C6:C7 translocates to the plasma membrane

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C5b:C6:C7 translocates to the plasma membrane Show undefined attributes

authored	[InstanceEdit:114498] de Bono, B, 2004-08-04 09:17:50
category	transition
compartment	[Compartment:947586] external side of plasma membrane
created	[InstanceEdit:173721] de Bono, B, 2006-02-16 12:12:29
dbId	173720
displayName	C5b:C6:C7 translocates to the plasma membrane
eventOf	[Pathway:R-HSA-166665] Terminal pathway of complement - Homo sapiens
followingEvent	[Reaction:R-HSA-173723] C8 binds C5b:C6:C7 - Homo sapiens
input	[Complex:R-HSA-173708] C5b:C6:C7 [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:173730] Molecular organization and function of the complement system
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	C5b:C6:C7 translocates to the plasma membrane
orthologousEvent	[Reaction:R-GGA-173720] C5b:C6:C7 translocates to the plasma membrane - Gallus gallus [Reaction:R-XTR-173720] C5b:C6:C7 translocates to the plasma membrane - Xenopus tropicalis [Reaction:R-SSC-173720] C5b:C6:C7 translocates to the plasma membrane - Sus scrofa [Reaction:R-BTA-173720] C5b:C6:C7 translocates to the plasma membrane - Bos taurus [Reaction:R-CFA-173720] C5b:C6:C7 translocates to the plasma membrane - Canis familiaris [Reaction:R-MMU-173720] C5b:C6:C7 translocates to the plasma membrane - Mus musculus
output	[Complex:R-HSA-173719] C5b:C6:C7 [plasma membrane]
precedingEvent	[Reaction:R-HSA-173709] C7 binds C5b:C6 - Homo sapiens
regulatedBy	[NegativeRegulation:R-HSA-8852766] Negative regulation by 'CLU:C5b:C6:C7, C8, C9 [extracellular region]'
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:181939] D'Eustachio, P, 2006-07-03 21:35:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-173720
summation	[Summation:8852730] C7 recruitment of C7 results in a weak association of C5b:C6...
updateTrackers	[UpdateTracker:9783602] Update Tracker - [Reaction:173720] C5b:C6:C7 translocates to the plasma membrane - v56:[addRegulator, addSummation]

Referrals

(updatedInstance)	[UpdateTracker:9783602] Update Tracker - [Reaction:173720] C5b:C6:C7 translocates to the plasma membrane - v56:[addRegulator, addSummation]
(hasEvent)	[Pathway:R-HSA-166665] Terminal pathway of complement
(precedingEvent)	[Reaction:R-HSA-173723] C8 binds C5b:C6:C7

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