C7 binds C5b:C6

Stable Identifier
R-HSA-173709
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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C7 binds C5b:C6
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The C5b:C6 complex binds C7. Normally the C5b:C6 complex remains bound to the C3/C5 convertase until it binds a single C7 molecule.

Literature References
PubMed ID Title Journal Year
3052276 Molecular organization and function of the complement system

Muller-Eberhard, HJ

Annu Rev Biochem 1988
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
CLU:C5b:C6:C7, C8, C9 [extracellular region] (Homo sapiens)
Orthologous Events
Formation of C5b:C6:C7 (Gallus gallus)
C5b:C6:C7 inserts into the target cell membrane (Gallus gallus)
C7 binds C5b:C6 (Bos taurus)
C7 binds C5b:C6 (Caenorhabditis elegans)
C7 binds C5b:C6 (Canis familiaris)
C7 binds C5b:C6 (Danio rerio)
C7 binds C5b:C6 (Gallus gallus)
C7 binds C5b:C6 (Mus musculus)
C7 binds C5b:C6 (Sus scrofa)
C7 binds C5b:C6 (Xenopus tropicalis)
Authored
de Bono, B  (2004-08-04)
Reviewed
D'Eustachio, P  (2006-07-04)
Created
de Bono, B  (2006-02-16)
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