Reactome | Binding and entry of HIV virion

Schema > Pathway > Entries

Binding and entry of HIV virion Show undefined attributes

authored	[InstanceEdit:176401] Morrow, MP, Bukrinsky, Michael, 2006-03-07
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:173116] Gopinathrao, G, 2006-02-07 19:48:25
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	173107
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Binding and entry of HIV virion
edited	[InstanceEdit:174499] Gopinathrao, G, 2006-02-17 18:35:46
eventOf	[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle - Homo sapiens
followingEvent	[Pathway:R-HSA-162585] Uncoating of the HIV Virion - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:160715] symbiont entry into host
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-164509] Binding of gp120 of ENV oligomer to the host CD4 - Homo sapiens [Reaction:R-HSA-164510] Conformational change in gp120 of Env oligomer - Homo sapiens [Reaction:R-HSA-164507] CD4:gp120 binds to chemokine co-receptor CCR5/CXCR4 - Homo sapiens [Reaction:R-HSA-164500] Conformational changes in gp120 exposes gp41 - Homo sapiens [Reaction:R-HSA-164515] Fusogenic activation of gp41 - Homo sapiens [Reaction:R-HSA-164521] Insertion of gp41 fusion peptide into the target membrane - Homo sapiens [Reaction:R-HSA-164508] N and C terminal heptad repeat helices of gp41 form six-helix bundle - Homo sapiens [Reaction:R-HSA-164524] Fusion of viral membrane with host cell membrane - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2016-12-21
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Binding and entry of HIV virion
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-07-31
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:181880] Reeves, J, 2006-06-12 15:22:40
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-173107
summation	[Summation:173461] HIV enters cells by fusion at the cell surface, that results...
updateTrackers	[UpdateTracker:9789800] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v37:[updateContainedRLE] [UpdateTracker:9782546] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v59:[updateContainedRLE] [UpdateTracker:9784843] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v53:[updateContainedRLE] [UpdateTracker:9783307] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v57:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9789800] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v37:[updateContainedRLE] [UpdateTracker:9782546] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v59:[updateContainedRLE] [UpdateTracker:9784843] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v53:[updateContainedRLE] [UpdateTracker:9783307] Update Tracker - [Pathway:173107] Binding and entry of HIV virion - v57:[updateContainedRLE]
(precedingEvent)	[Pathway:R-HSA-162585] Uncoating of the HIV Virion
(hasEvent)	[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle