Reactome | Fusogenic activation of gp41

Schema > Reaction > Entries

Fusogenic activation of gp41 Show undefined attributes

authored	[InstanceEdit:176401] Morrow, MP, Bukrinsky, Michael, 2006-03-07
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:164501] D'Eustachio, P, 2005-05-24 15:07:45
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	164515
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Fusogenic activation of gp41
edited	[InstanceEdit:174499] Gopinathrao, G, 2006-02-17 18:35:46
eventOf	[Pathway:R-HSA-173107] Binding and entry of HIV virion - Homo sapiens
followingEvent	[Reaction:R-HSA-164521] Insertion of gp41 fusion peptide into the target membrane - Homo sapiens
input	[Complex:R-HSA-173665] Virion with gp41 exposed [extracellular region]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:175738] Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41 [LiteratureReference:175604] Requirement of N-terminal amino acid residues of gp41 for human immunodeficiency virus type 1-mediated cell fusion [LiteratureReference:175780] Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Fusogenic activation of gp41 gp41 N terminal fusion peptide released from viral membrane
output	[Complex:R-HSA-173639] Virion with fusogenically activated gp41 [extracellular region]
precedingEvent	[Reaction:R-HSA-164500] Conformational changes in gp120 exposes gp41 - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-08-02
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:181880] Reeves, J, 2006-06-12 15:22:40
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-164515
summation	[Summation:177627] Fusion of HIV with target cell plasma membranes is mediated ...
updateTrackers	[UpdateTracker:9783310] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v57:[modifyText] [UpdateTracker:9782452] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v59:[modifyText] [UpdateTracker:9784772] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v53:[modifyText] [UpdateTracker:9789742] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v37:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9783310] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v57:[modifyText] [UpdateTracker:9782452] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v59:[modifyText] [UpdateTracker:9784772] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v53:[modifyText] [UpdateTracker:9789742] Update Tracker - [Reaction:164515] Fusogenic activation of gp41 - v37:[modifyText]
(precedingEvent)	[Reaction:R-HSA-164521] Insertion of gp41 fusion peptide into the target membrane
(hasEvent)	[Pathway:R-HSA-173107] Binding and entry of HIV virion