Reactome | HCK [cytosol]

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HCK [cytosol] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-912625] FYN-like kinases [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-200872] Hck-1:Nef [cytosol] - Homo sapiens [Complex:R-HSA-9609280] Active FLT3:HCK [plasma membrane] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-9609274] Active FLT3 binds HCK - Homo sapiens [Reaction:R-HSA-200858] Nef Binds and activates the Src-family tyrosine kinase Hck - Homo sapiens [BlackBoxEvent:R-HSA-9676071] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK - Homo sapiens
created	[InstanceEdit:167707] Gillespie, ME, 2005-11-01 21:41:07
dbId	167708
displayName	HCK [cytosol]
endCoordinate	526
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-167708] HCK [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-167708] HCK [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-167708] HCK [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-167708] HCK [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-167708] HCK [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-167708] HCK [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-167708] HCK [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-167708] HCK [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-CEL-167708] HCK [cytosol] - Caenorhabditis elegans
maxDepth	1
memberOf	[DefinedSet:R-HSA-9817990] FYN,HCK,SRC,YES1 [cytosol] - Homo sapiens [DefinedSet:R-HSA-1861597] Src family kinases (SFKs) [cytosol] - Homo sapiens
modified	[InstanceEdit:4084660] Orlic-Milacic, M, 2013-07-30
name	HCK Hck-1
referenceEntity	[ReferenceGeneProduct:uniprot:P08631] UniProt:P08631 HCK
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-167708
startCoordinate	2
updateTrackers	[UpdateTracker:9877567] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v44:[addEndCoordinate, addStartCoordinate] [UpdateTracker:9887827] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v46:[removeName] [UpdateTracker:9885249] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v45:[addName] [UpdateTracker:9869776] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v34:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9877567] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v44:[addEndCoordinate, addStartCoordinate] [UpdateTracker:9887827] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v46:[removeName] [UpdateTracker:9885249] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v45:[addName] [UpdateTracker:9869776] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v34:[addName]
(hasMember)	[DefinedSet:R-HSA-9817990] FYN,HCK,SRC,YES1 [cytosol] [DefinedSet:R-HSA-1861597] Src family kinases (SFKs) [cytosol]
(input)	[BlackBoxEvent:R-HSA-9676071] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK [BlackBoxEvent:R-HSA-9609274] Active FLT3 binds HCK [Reaction:R-HSA-200858] Nef Binds and activates the Src-family tyrosine kinase Hck
(hasComponent)	[Complex:R-HSA-9609280] Active FLT3:HCK [plasma membrane] [Complex:R-HSA-200872] Hck-1:Nef [cytosol]
(hasCandidate)	[CandidateSet:R-HSA-912625] FYN-like kinases [cytosol]

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