Reactome | Association of Tat with P-TEFb(Cyclin T1:Cdk9)

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167236] Matthews, L, 2005-10-13 20:01:32
dbId	167234
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Association of Tat with P-TEFb(Cyclin T1:Cdk9)
eventOf	[Pathway:R-HSA-167200] Formation of HIV-1 elongation complex containing HIV-1 Tat - Homo sapiens [Pathway:R-HSA-176034] Interactions of Tat with host cellular proteins - Homo sapiens
input	[Complex:R-HSA-167183] P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] [EntityWithAccessionedSequence:R-HIV-175856] Tat (P04608) [nucleoplasm]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:170692] Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of Tat with P-TEFb(Cyclin T1:Cdk9)
output	[Complex:R-HSA-167237] Tat:P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm]
precedingEvent	[Reaction:R-HSA-167235] Formation of the P-TEFb(Cyclin T1:Cdk9) complex - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-167234
summation	[Summation:167896] Tat associates with the Cyclin T1 subunit of P-TEFb (Cyclin ...

(hasEvent)

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