Reactome | p14ARF [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

p14ARF [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:4568910] SUMO transferase activity of p14ARF [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-3209192] p14-ARF:MDM2 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9761836] p14ARF binds NFE2L2:CREBBP, EP300 - Homo sapiens [Reaction:R-HSA-6804998] p14ARF forms a ternary complex with MDM2 and TP53 - Homo sapiens
created	[InstanceEdit:1629812] Orlic-Milacic, M, 2011-10-03
dbId	1629813
displayName	p14ARF [nucleoplasm]
endCoordinate	132
inDisease	false
inferredTo	[GenomeEncodedEntity:R-MMU-1629813] Ghost homologue of p14ARF [nucleoplasm] - Mus musculus [GenomeEncodedEntity:R-RNO-1629813] Ghost homologue of p14ARF [nucleoplasm] - Rattus norvegicus [GenomeEncodedEntity:R-CFA-1629813] Ghost homologue of p14ARF [nucleoplasm] - Canis familiaris [GenomeEncodedEntity:R-DRE-1629813] Ghost homologue of p14ARF [nucleoplasm] - Danio rerio
maxDepth	1
modified	[InstanceEdit:9645195] Orlic-Milacic, Marija, 2019-05-06
name	p14ARF Cyclin-dependent kinase inhibitor 2A, isoform 4 p19ARF
negativelyRegulates	[NegativeRegulation:R-HSA-8952385] Negative regulation by 'p14-ARF [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-HSA-9645672] p14ARF translocates to the nucleus - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q8N726] UniProt:Q8N726 CDKN2A
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1629813
startCoordinate	1
updateTrackers	[UpdateTracker:9900584] Update Tracker - [EntityWithAccessionedSequence:1629813] p14ARF [nucleoplasm] - v69:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9900584] Update Tracker - [EntityWithAccessionedSequence:1629813] p14ARF [nucleoplasm] - v69:[modifyName]
(physicalEntity)	[CatalystActivity:4568910] SUMO transferase activity of p14ARF [nucleoplasm]
(hasComponent)	[Complex:R-HSA-3209192] p14-ARF:MDM2 [nucleoplasm] [Complex:R-HSA-9761732] p-NFE2L2:CREBBP,EP300;p14ARF [nucleoplasm] [Complex:R-HSA-6804999] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4:TP53 [nucleoplasm] [Complex:R-HSA-6804995] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm]
(input)	[Reaction:R-HSA-9761836] p14ARF binds NFE2L2:CREBBP, EP300 [Reaction:R-HSA-6804998] p14ARF forms a ternary complex with MDM2 and TP53
(activeUnit)	[NegativeRegulation:9761805] Negative regulation by 'p-NFE2L2:CREBBP,EP300;p14ARF [nucleoplasm]' [NegativeRegulation:R-HSA-8979105] Negative regulation by 'p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm]'
(regulator)	[NegativeRegulation:R-HSA-8952385] Negative regulation by 'p14-ARF [nucleoplasm]'
(output)	[BlackBoxEvent:R-HSA-9645672] p14ARF translocates to the nucleus