Reactome | p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6804997] Orlic-Milacic, Marija, 2015-10-16
dbId	6804995
displayName	p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm]
hasComponent	[DefinedSet:R-HSA-6804745] p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1629813] p14ARF [nucleoplasm]
inDisease	false
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9645195] Orlic-Milacic, Marija, 2019-05-06
name	p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4
negativelyRegulates	[NegativeRegulation:R-HSA-8979105] Negative regulation by 'p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-6804996] p14ARF sequesters MDM2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6804995
updateTrackers	[UpdateTracker:9900411] Update Tracker - [Complex:6804995] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm] - v69:[modifyName] [UpdateTracker:9894887] Update Tracker - [Complex:6804995] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm] - v58:[modifyName, updateContainedComponent]

(updatedInstance)	[UpdateTracker:9900411] Update Tracker - [Complex:6804995] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm] - v69:[modifyName] [UpdateTracker:9894887] Update Tracker - [Complex:6804995] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm] - v58:[modifyName, updateContainedComponent]
(output)	[Reaction:R-HSA-6804996] p14ARF sequesters MDM2
(regulator)	[NegativeRegulation:R-HSA-8979105] Negative regulation by 'p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm]'

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