Reactome | WWTR1 [nucleoplasm]

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WWTR1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-2064919] RUNX2:WWTR1(TAZ) [nucleoplasm] - Homo sapiens [Complex:R-HSA-9618554] TEAD1:WWTR1 [nucleoplasm] - Homo sapiens [Complex:R-HSA-2032799] TBX5:WWTR1:PCAF [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-2064932] WWTR1 (TAZ) binds RUNX2 - Homo sapiens [Reaction:R-HSA-2032794] WWTR1 (TAZ), TBX5, and PCAF form a complex - Homo sapiens [Reaction:R-HSA-2032781] WWTR1 (TAZ) binds TEAD - Homo sapiens
created	[InstanceEdit:1629776] Orlic-Milacic, M, 2011-10-03
dbId	1629775
displayName	WWTR1 [nucleoplasm]
endCoordinate	400
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-1629775] Wwtr1 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-1629775] Wwtr1 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-1629775] WWTR1 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-1629775] WWTR1 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-1629775] WWTR1 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-1629775] wwtr1 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-1629775] wwtr1 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-1629775] WWTR1 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-1629775] yki [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-1629775] yap-1 [nucleoplasm] - Caenorhabditis elegans
maxDepth	1
name	WWTR1 WW domain-containing transcription regulator protein 1 Transcriptional coactivator with PDZ-binding motif TAZ
producedByEvent	[Reaction:R-HSA-2032768] Translocation of WWTR1 (TAZ) to the nucleus - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q9GZV5] UniProt:Q9GZV5 WWTR1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1629775
startCoordinate	1

Referrals

(hasComponent)	[Complex:R-HSA-9618554] TEAD1:WWTR1 [nucleoplasm] [Complex:R-HSA-2064919] RUNX2:WWTR1(TAZ) [nucleoplasm] [Complex:R-HSA-2032799] TBX5:WWTR1:PCAF [nucleoplasm] [Complex:R-HSA-2032762] TEAD:WWTR1(TAZ) [nucleoplasm] [Complex:R-HSA-2106580] WWTR1:p-2S-SMAD2,3:SMAD4 [nucleoplasm]
(activeUnit)	[PositiveGeneExpressionRegulation:9618565] Positive gene expression regulation by 'PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm]'
(input)	[Reaction:R-HSA-2064932] WWTR1 (TAZ) binds RUNX2 [Reaction:R-HSA-2032794] WWTR1 (TAZ), TBX5, and PCAF form a complex [Reaction:R-HSA-2032781] WWTR1 (TAZ) binds TEAD
(output)	[Reaction:R-HSA-2032768] Translocation of WWTR1 (TAZ) to the nucleus

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