Reactome | RUNX2:WWTR1(TAZ) [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8985224] RUNX2:WWTR1:BGLAP gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8985227] The complex of RUNX2 and WWTR1 (TAZ) binds the BGLAP gene promoter - Homo sapiens
created	[InstanceEdit:2064921] D'Eustachio, P, 2012-01-19
dbId	2064919
displayName	RUNX2:WWTR1(TAZ) [nucleoplasm]
goCellularComponent	[GO_CellularComponent:7658] transcription regulator complex
hasComponent	[CandidateSet:R-HSA-9007751] RUNX2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1629775] WWTR1 [nucleoplasm]
inDisease	false
isChimeric	false
maxDepth	3
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	RUNX2:WWTR1(TAZ)
producedByEvent	[Reaction:R-HSA-2064932] WWTR1 (TAZ) binds RUNX2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2064919
updateTrackers	[UpdateTracker:9897639] Update Tracker - [Complex:2064919] RUNX2:WWTR1(TAZ) [nucleoplasm] - v62:[add_removeHasComponent]

(updatedInstance)	[UpdateTracker:9897639] Update Tracker - [Complex:2064919] RUNX2:WWTR1(TAZ) [nucleoplasm] - v62:[add_removeHasComponent]
(activeUnit)	[PositiveGeneExpressionRegulation:R-HSA-8985240] Positive gene expression regulation by 'RUNX2:WWTR1:BGLAP gene [nucleoplasm]'
(output)	[Reaction:R-HSA-2064932] WWTR1 (TAZ) binds RUNX2
(hasComponent)	[Complex:R-HSA-8985224] RUNX2:WWTR1:BGLAP gene [nucleoplasm]
(input)	[Reaction:R-HSA-8985227] The complex of RUNX2 and WWTR1 (TAZ) binds the BGLAP gene promoter

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