Reactome | Myristoylation of Nef

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:167549] myristoyltransferase activity of NMT 1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:162913] Joshi-Tope, G, 2005-04-06 02:39:59
dbId	162914
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Myristoylation of Nef
edited	[InstanceEdit:3621683] Gillespie, ME, 2013-05-23
eventOf	[Pathway:R-HSA-162599] Late Phase of HIV Life Cycle - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:2145] N-terminal protein myristoylation
input	[SimpleEntity:R-ALL-184174] MYS-CoA [cytosol] [EntityWithAccessionedSequence:R-HIV-165575] nef [cytosol]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:167501] Human N-myristoyltransferases form stable complexes with lentiviral nef and other viral and cellular substrate proteins
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Myristoylation of Nef
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [EntityWithAccessionedSequence:R-HIV-167605] myristoylated nef [cytosol]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-162914
summation	[Summation:167612] Nef amino terminal myristoylation has been shown to be criti...

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