Reactome | FGFR4 Y367C [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2011955] FGFR4 Y367C mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2011955] FGFR4 Y367C mutant dimer [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-2012086] Constitutive dimerization of FGFR4 Y367C mutant - Homo sapiens [Reaction:R-HSA-2012086] Constitutive dimerization of FGFR4 Y367C mutant - Homo sapiens
created	[InstanceEdit:1614440] Rothfels, K, 2011-09-28
crossReference	[DatabaseIdentifier:12020748] Mondo:0007254
dbId	1614439
disease	[Disease:1500576] breast cancer
displayName	FGFR4 Y367C [plasma membrane]
endCoordinate	802
hasModifiedResidue	[ReplacedResidue:1614438] L-tyrosine 367 replaced with L-cysteine
inDisease	true
maxDepth	1
modified	[InstanceEdit:8877159] Rothfels, Karen, 2016-06-21
name	FGFR4 Y367C
referenceEntity	[ReferenceGeneProduct:uniprot:P22455] UniProt:P22455 FGFR4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1614439
startCoordinate	22
updateTrackers	[UpdateTracker:9889997] Update Tracker - [EntityWithAccessionedSequence:1614439] FGFR4 Y367C [plasma membrane] - v52:[modifyName] [UpdateTracker:9894823] Update Tracker - [EntityWithAccessionedSequence:1614439] FGFR4 Y367C [plasma membrane] - v58:[removeInferredFrom]

(updatedInstance)	[UpdateTracker:9889997] Update Tracker - [EntityWithAccessionedSequence:1614439] FGFR4 Y367C [plasma membrane] - v52:[modifyName] [UpdateTracker:9894823] Update Tracker - [EntityWithAccessionedSequence:1614439] FGFR4 Y367C [plasma membrane] - v58:[removeInferredFrom]
(hasComponent)	[Complex:R-HSA-2011955] FGFR4 Y367C mutant dimer [plasma membrane]
(input)	[Reaction:R-HSA-2012086] Constitutive dimerization of FGFR4 Y367C mutant
(diseaseEntity)	[EntityFunctionalStatus:5654481] gain_of_function of FGFR4 Y367C [plasma membrane]

Cite Us!