Reactome | miR-34 RISC [cytosol]

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miR-34 RISC [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9925250] CD274 mRNA:miR-34 RISC [cytosol] - Homo sapiens [Complex:R-HSA-1606698] NOTCH1 mRNA:miR-34 RISC [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-1912367] MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA - Homo sapiens [Reaction:R-HSA-9924921] CD274 mRNA binds miR-34 RISC - Homo sapiens [Reaction:R-HSA-1606682] MIR34 microRNAs bind 3'UTR of NOTCH1 mRNA - Homo sapiens
created	[InstanceEdit:1606691] Orlic-Milacic, M, 2011-09-23
dbId	1606685
displayName	miR-34 RISC [cytosol]
hasMember	[Complex:R-HSA-1606684] miR-34 Endonucleolytic RISC [cytosol] - Homo sapiens [Complex:R-HSA-1606692] miR-34 Nonendonucleolytic RISC [cytosol] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-1606685] miR-34 RISC [cytosol] - Mus musculus [DefinedSet:R-RNO-1606685] miR-34 RISC [cytosol] - Rattus norvegicus [DefinedSet:R-CFA-1606685] miR-34 RISC [cytosol] - Canis familiaris [DefinedSet:R-BTA-1606685] miR-34 RISC [cytosol] - Bos taurus [DefinedSet:R-SSC-1606685] miR-34 RISC [cytosol] - Sus scrofa [Complex:R-DRE-1606692] miR-34 Nonendonucleolytic RISC [cytosol] - Danio rerio [DefinedSet:R-XTR-1606685] miR-34 RISC [cytosol] - Xenopus tropicalis [DefinedSet:R-GGA-1606685] miR-34 RISC [cytosol] - Gallus gallus
maxDepth	5
modified	[InstanceEdit:1614227] Orlic-Milacic, M, 2011-09-27
name	miR-34 RISC miR-34-induced Silencing Complex
producedByEvent	[BlackBoxEvent:R-HSA-1912406] p53 positively regulates transcription of MIR34 microRNAs - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-1606685
updateTrackers	[UpdateTracker:9895927] Update Tracker - [DefinedSet:1606685] miR-34 RISC [cytosol] - v60:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9895927] Update Tracker - [DefinedSet:1606685] miR-34 RISC [cytosol] - v60:[updateContainedMemberOrCandidate]
(input)	[Reaction:R-HSA-9924921] CD274 mRNA binds miR-34 RISC [Reaction:R-HSA-1912367] MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA [Reaction:R-HSA-1606682] MIR34 microRNAs bind 3'UTR of NOTCH1 mRNA
(hasComponent)	[Complex:R-HSA-9925250] CD274 mRNA:miR-34 RISC [cytosol] [Complex:R-HSA-1606698] NOTCH1 mRNA:miR-34 RISC [cytosol] [Complex:R-HSA-1911490] NOTCH2 mRNA:miR-34 RISC [cytosol]
(activeUnit)	[NegativeRegulation:9925033] Negative regulation by 'CD274 mRNA:miR-34 RISC [cytosol]' [NegativeRegulation:R-HSA-1980089] Negative regulation by 'NOTCH1 mRNA:miR-34 RISC [cytosol]' [NegativeRegulation:R-HSA-1980097] Negative regulation by 'NOTCH2 mRNA:miR-34 RISC [cytosol]'
(output)	[BlackBoxEvent:R-HSA-1912406] p53 positively regulates transcription of MIR34 microRNAs

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