Reactome | MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA

Schema > Reaction > Entries

MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA Show undefined attributes

authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1606560] Orlic-Milacic, M, 2011-09-22
dbId	1606561
displayName	MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2121209] May, B, 2012-02-09 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06 [InstanceEdit:1609686] Jupe, S, 2011-09-27 [InstanceEdit:2121211] Gillespie, ME, 2012-02-09
eventOf	[Pathway:R-HSA-1912408] Pre-NOTCH Transcription and Translation - Homo sapiens
input	[DefinedSet:R-HSA-1606557] miR-449 RISC [cytosol] [EntityWithAccessionedSequence:R-HSA-1606559] NOTCH1 mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1606546] Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway
maxDepth	1
modified	[InstanceEdit:9927655] Orlic-Milacic, Marija, 2024-11-08
name	MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA
negativePrecedingEvent	[NegativePrecedingEvent:9927649] Negative relationship: NOTCH1 and NOTCH4 gene transcription is inhibited by SIRT6
output	[Complex:R-HSA-1606562] NOTCH1 mRNA:miR-449 RISC [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-1912416] NOTCH1 gene transcription - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1606561
summation	[Summation:1606558] Translation of NOTCH1 mRNA is negatively regulated by MIR449...

Referrals

(hasEvent)

[Pathway:R-HSA-1912408] Pre-NOTCH Transcription and Translation

Cite Us!