Reactome | dsDNA:ZBP1 [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-3465595] dsDNA:ZBP1:pS-172,K48polyUb-TBK1 [cytosol] - Homo sapiens [Complex:R-HSA-1810470] dsDNA:ZBP1:RIP1:RIP3 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-1606324] Recruitment TBK1 to dsDNA:ZBP1 followed by its activation - Homo sapiens [Reaction:R-HSA-1810457] ZBP1(DAI) recruits RIP1 and RIP3 - Homo sapiens
created	[InstanceEdit:1591227] Shamovsky, V, 2011-09-08
crossReference	[DatabaseIdentifier:12020762] Mondo:0005108
dbId	1591233
disease	[Disease:3134794] viral infectious disease
displayName	dsDNA:ZBP1 [cytosol]
hasComponent	[DefinedSet:R-NUL-8982083] ZBP1 ligand [cytosol] [Complex:R-HSA-1591226] ZBP1:ZBP1 [cytosol]
inDisease	true
isChimeric	false
maxDepth	3
modified	[InstanceEdit:9013883] Shamovsky, Veronica, 2017-07-26
name	dsDNA:ZBP1
producedByEvent	[Reaction:R-HSA-1591234] ZBP1 binds cytosolic DNA - Homo sapiens
relatedSpecies	[Species:8982084] Human alphaherpesvirus 2 [Species:2671791] Human cytomegalovirus
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1591233
updateTrackers	[UpdateTracker:9887076] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v45:[addDisease, modifyName, updateContainedComponent] [UpdateTracker:9897608] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v62:[add_removeHasComponent, removeDisease] [UpdateTracker:9871573] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v40:[updateContainedComponent] [UpdateTracker:9876643] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v44:[add_removeHasComponent]

(updatedInstance)	[UpdateTracker:9887076] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v45:[addDisease, modifyName, updateContainedComponent] [UpdateTracker:9897608] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v62:[add_removeHasComponent, removeDisease] [UpdateTracker:9871573] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v40:[updateContainedComponent] [UpdateTracker:9876643] Update Tracker - [Complex:1591233] dsDNA:ZBP1 [cytosol] - v44:[add_removeHasComponent]
(input)	[Reaction:R-HSA-1606324] Recruitment TBK1 to dsDNA:ZBP1 followed by its activation [Reaction:R-HSA-1810457] ZBP1(DAI) recruits RIP1 and RIP3
(hasComponent)	[Complex:R-HSA-3465595] dsDNA:ZBP1:pS-172,K48polyUb-TBK1 [cytosol] [Complex:R-HSA-1606333] dsDNA:ZBP1:pS-172-TBK1 [cytosol] [Complex:R-HSA-1810470] dsDNA:ZBP1:RIP1:RIP3 [cytosol]
(output)	[Reaction:R-HSA-1591234] ZBP1 binds cytosolic DNA

dsDNA:ZBP1 [cytosol] Show undefined attributes

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