Reactome | NICD2 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-157933] NICD2 traffics to the nucleus - Homo sapiens
created	[InstanceEdit:157631] Jassal, B, 2005-01-04 16:01:41
dbId	157642
displayName	NICD2 [cytosol]
endCoordinate	2471
inDisease	false
maxDepth	1
modified	[InstanceEdit:3325515] Orlic-Milacic, M, 2013-05-09
name	NICD2 NOTCH2(1697-2471) NICD 2 fragment N2ICD
producedByEvent	[Reaction:R-HSA-157640] NEXT2 is cleaved to produce NICD2 - Homo sapiens [BlackBoxEvent:R-HSA-2974731] Gamma-secretase cleaves CNTN1:NOTCH2 to release NICD2 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q04721] UniProt:Q04721 NOTCH2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-157642
startCoordinate	1697
updateTrackers	[UpdateTracker:9882917] Update Tracker - [EntityWithAccessionedSequence:157642] NICD2 [cytosol] - v45:[addName] [UpdateTracker:9870689] Update Tracker - [EntityWithAccessionedSequence:157642] NICD2 [cytosol] - v38:[addName] [UpdateTracker:9871917] Update Tracker - [EntityWithAccessionedSequence:157642] NICD2 [cytosol] - v41:[addName]

(updatedInstance)	[UpdateTracker:9882917] Update Tracker - [EntityWithAccessionedSequence:157642] NICD2 [cytosol] - v45:[addName] [UpdateTracker:9870689] Update Tracker - [EntityWithAccessionedSequence:157642] NICD2 [cytosol] - v38:[addName] [UpdateTracker:9871917] Update Tracker - [EntityWithAccessionedSequence:157642] NICD2 [cytosol] - v41:[addName]
(input)	[Reaction:R-HSA-157933] NICD2 traffics to the nucleus
(output)	[Reaction:R-HSA-157640] NEXT2 is cleaved to produce NICD2 [BlackBoxEvent:R-HSA-2974731] Gamma-secretase cleaves CNTN1:NOTCH2 to release NICD2

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