Reactome | EEF2 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

EEF2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-156922] eEF2:GDP [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8932243] EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 - Homo sapiens [Reaction:R-HSA-5336421] DT fragment A ADP-ribosylates target cell EEF - Homo sapiens [Reaction:R-HSA-156930] GTP-binding activates eEF2 - Homo sapiens
created	[InstanceEdit:156906] Gopinathrao, G, 2004-12-14 18:38:21
dbId	156901
displayName	EEF2 [cytosol]
endCoordinate	858
hasModifiedResidue	[ModifiedResidue:5334752] dipthamide at 715
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-156901] EEF2 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-156901] EEF2 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-156901] EEF2 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-156901] EEF2 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-156901] EEF2 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-156901] eef2l2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DRE-156901-2] eef2a.1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DRE-156901-3] eef2a.2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DRE-156901-4] EEF2 [cytosol] - Danio rerio [DefinedSet:R-DRE-156901-5] Homologues of EEF2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-156901] eef2 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-156901] EEF2 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-156901] EEF2 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-156901] EEF2 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-156901] EEF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-156901-2] cinC [cytosol] - Dictyostelium discoideum [DefinedSet:R-DDI-156901-3] Homologues of EEF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-156901] EEF2 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-156901] EEF2 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-156901] EEF2 [cytosol] - Plasmodium falciparum
literatureReference	[LiteratureReference:5334749] ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products [LiteratureReference:5334758] ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products
maxDepth	1
modified	[InstanceEdit:5358503] D'Eustachio, Peter, 2014-03-28
name	EEF2 diphthamide EEF2 eEF2
producedByEvent	[Reaction:R-HSA-5358475] DPH6 ligates ammonium to diphthine-EEF2 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P13639] UniProt:P13639 EEF2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-156901
startCoordinate	2
updateTrackers	[UpdateTracker:9876901] Update Tracker - [EntityWithAccessionedSequence:156901] EEF2 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate] [UpdateTracker:9887345] Update Tracker - [EntityWithAccessionedSequence:156901] EEF2 [cytosol] - v45:[addName] [UpdateTracker:9889553] Update Tracker - [EntityWithAccessionedSequence:156901] EEF2 [cytosol] - v49:[addHasModifiedResidue, addLiteratureReference, addName]

Referrals

(updatedInstance)	[UpdateTracker:9876901] Update Tracker - [EntityWithAccessionedSequence:156901] EEF2 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate] [UpdateTracker:9887345] Update Tracker - [EntityWithAccessionedSequence:156901] EEF2 [cytosol] - v45:[addName] [UpdateTracker:9889553] Update Tracker - [EntityWithAccessionedSequence:156901] EEF2 [cytosol] - v49:[addHasModifiedResidue, addLiteratureReference, addName]
(input)	[Reaction:R-HSA-8932243] EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 [Reaction:R-HSA-5336421] DT fragment A ADP-ribosylates target cell EEF [Reaction:R-HSA-156930] GTP-binding activates eEF2
(output)	[Reaction:R-HSA-5358475] DPH6 ligates ammonium to diphthine-EEF2
(hasComponent)	[Complex:R-HSA-156922] eEF2:GDP [cytosol] [Complex:R-HSA-156916] eEF2:GTP [cytosol]

Cite Us!