Reactome | SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm]

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SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1535900] May, B, 2011-08-26
dbId	1535906
displayName	SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-199305] FOXO3 [nucleoplasm] [OtherEntity:R-ALL-1535904] FoxO3a-binding Element [nucleoplasm] [DefinedSet:R-HSA-173511] p-2S-SMAD2,3:SMAD4 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Mus musculus [Complex:R-RNO-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Canis familiaris [Complex:R-BTA-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Bos taurus [Complex:R-SSC-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Sus scrofa [Complex:R-XTR-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Xenopus tropicalis [Complex:R-DME-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Caenorhabditis elegans
isChimeric	false
literatureReference	[LiteratureReference:1535902] Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells
maxDepth	4
modified	[InstanceEdit:5262813] May, B, 2014-02-07
name	SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element
producedByEvent	[Reaction:R-HSA-1535903] Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1535906
updateTrackers	[UpdateTracker:9872021] Update Tracker - [Complex:1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - v41:[updateContainedComponent] [UpdateTracker:9902542] Update Tracker - [Complex:1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - v78:[updateContainedComponent] [UpdateTracker:9889191] Update Tracker - [Complex:1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - v48:[modifyName] [UpdateTracker:9875258] Update Tracker - [Complex:1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - v44:[updateContainedComponent]

Referrals

(updatedInstance)

(output)

[Reaction:R-HSA-1535903] Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements

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