Reactome | SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10492946
displayName	SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-SSC-199305] FOXO3 [nucleoplasm] [OtherEntity:R-ALL-1535904] FoxO3a-binding Element [nucleoplasm] [Complex:R-SSC-8878153] p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] - Homo sapiens
maxDepth	3
name	SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element
producedByEvent	[Reaction:R-SSC-1535903] Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-1535906
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-SSC-1535903] Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements
(inferredTo)	[Complex:R-HSA-1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm]

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