Reactome | GPCho is hydrolyzed to Cho and G3P by GPCPD1

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GPCho is hydrolyzed to Cho and G3P by GPCPD1 Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524092] glycerophosphodiester phosphodiesterase activity of GPCPD1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
crossReference	[DatabaseIdentifier:12667443] RHEA:16062
dbId	1483116
displayName	GPCho is hydrolyzed to Cho and G3P by GPCPD1
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483115] Hydrolysis of LPC - Homo sapiens
followingEvent	[Reaction:R-HSA-549112] G3P is acylated to 1-acyl LPA by AGPAT6 - Homo sapiens [Reaction:R-HSA-1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) - Homo sapiens [Reaction:R-HSA-1483004] Cho is phosphorylated to PCho by CHK dimer - Homo sapiens [Reaction:R-HSA-264622] Cho is acetylated to AcCho by CHAT - Homo sapiens
inferredFrom	[Reaction:R-MMU-1483112] GPCho is hydrolyzed to Cho and G3P by Gpcpd1 - Mus musculus
input	[SimpleEntity:R-ALL-1498750] GPCho [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:1601989] Complete sequencing and characterization of 21,243 full-length human cDNAs
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GPCho is hydrolyzed to Cho and G3P by GPCPD1
output	[SimpleEntity:R-ALL-264618] Cho [cytosol] [SimpleEntity:R-ALL-76114] G3P [cytosol]
precedingEvent	[Reaction:R-HSA-1482685] 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Homo sapiens [Reaction:R-HSA-1482696] 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C - Homo sapiens [Reaction:R-HSA-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Homo sapiens [Reaction:R-HSA-1482629] 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C - Homo sapiens [Reaction:R-HSA-8952251] PLA2G15 hydrolyses LPC to GPCho and LCFA(-) - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1483116
summation	[Summation:1483117] In the cytosol, glycerophosphocholine phosphodiesterase (GPC...

Referrals

(hasEvent)	[Pathway:R-HSA-1483115] Hydrolysis of LPC
(precedingEvent)	[Reaction:R-HSA-264622] Cho is acetylated to AcCho by CHAT [Reaction:R-HSA-549112] G3P is acylated to 1-acyl LPA by AGPAT6 [Reaction:R-HSA-1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) [Reaction:R-HSA-1483004] Cho is phosphorylated to PCho by CHK dimer
(inferredTo)	[Reaction:R-MMU-1483112] GPCho is hydrolyzed to Cho and G3P by Gpcpd1

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