Reactome | Cho is phosphorylated to PCho by CHK dimer

Schema > Reaction > Entries

Cho is phosphorylated to PCho by CHK dimer Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524073] choline kinase activity of CHK dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1483038] Williams, MG, 2011-08-12
dbId	1483004
displayName	Cho is phosphorylated to PCho by CHK dimer
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483191] Synthesis of PC - Homo sapiens
followingEvent	[Reaction:R-HSA-1483159] PCho is dephosphorylated to Cho by PHOSPHO1 - Homo sapiens [Reaction:R-HSA-1483081] PCho and CTP are condensed to CDP-Cho by PCYT1 dimer - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-264618] Cho [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1483009] Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment [LiteratureReference:1483015] Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Cho is phosphorylated to PCho by CHK dimer
orthologousEvent	[Reaction:R-RNO-1483004] Cho is phosphorylated to PCho by CHK dimer - Rattus norvegicus [Reaction:R-CFA-1483004] Cho is phosphorylated to PCho by CHK dimer - Canis familiaris [Reaction:R-BTA-1483004] Cho is phosphorylated to PCho by CHK dimer - Bos taurus [Reaction:R-PFA-1483004] Cho is phosphorylated to PCho by CHK dimer - Plasmodium falciparum [Reaction:R-SSC-1483004] Cho is phosphorylated to PCho by CHK dimer - Sus scrofa [Reaction:R-CEL-1483004] Cho is phosphorylated to PCho by CHK dimer - Caenorhabditis elegans [Reaction:R-DME-1483004] Cho is phosphorylated to PCho by CHK dimer - Drosophila melanogaster [Reaction:R-XTR-1483004] Cho is phosphorylated to PCho by CHK dimer - Xenopus tropicalis [Reaction:R-SCE-1483004] Cho is phosphorylated to PCho by CHK dimer - Saccharomyces cerevisiae [Reaction:R-SPO-1483004] Cho is phosphorylated to PCho by CHK dimer - Schizosaccharomyces pombe [Reaction:R-GGA-1483004] Cho is phosphorylated to PCho by CHK dimer - Gallus gallus [Reaction:R-MMU-1483004] Cho is phosphorylated to PCho by CHK dimer - Mus musculus [Reaction:R-DRE-1483004] Cho is phosphorylated to PCho by CHK dimer - Danio rerio
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-1524071] PCho [cytosol]
precedingEvent	[Reaction:R-HSA-1483159] PCho is dephosphorylated to Cho by PHOSPHO1 - Homo sapiens [Reaction:R-HSA-1483182] PC is hydrolyzed to PA and choline by PLD1/2 - Homo sapiens [Reaction:R-HSA-444433] Cho transports from the extracellular space to the cytosol - Homo sapiens [Reaction:R-HSA-1483116] GPCho is hydrolyzed to Cho and G3P by GPCPD1 - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1483004
summation	[Summation:1483030] In the cytosol, choline kinase alpha subunit (CHKA) homodime...

Referrals

(hasEvent)	[Pathway:R-HSA-1483191] Synthesis of PC
(precedingEvent)	[Reaction:R-HSA-1483159] PCho is dephosphorylated to Cho by PHOSPHO1 [Reaction:R-HSA-1483081] PCho and CTP are condensed to CDP-Cho by PCYT1 dimer

Cite Us!