Reactome | Translocation of tBID to mitochondria

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Translocation of tBID to mitochondria Show undefined attributes

category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:139911] Hardwick, JM, Tsujimoto, Y, 2004-08-09 19:10:09
dbId	139920
deleted	[Deleted:622301] Deletion of instance: 114267
displayName	Translocation of tBID to mitochondria
eventOf	[Pathway:R-HSA-75108] Activation, myristolyation of BID and translocation to mitochondria - Homo sapiens
followingEvent	[Reaction:R-HSA-508162] BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL - Homo sapiens [Reaction:R-HSA-114352] Sequestration of tBID by BCL-2 - Homo sapiens [Reaction:R-HSA-168848] tBID binds to inactive BAK protein - Homo sapiens [Reaction:R-HSA-508163] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 - Homo sapiens [Reaction:R-HSA-114284] Release of Cytochrome c from mitochondria - Homo sapiens [Reaction:R-HSA-114307] Release of SMAC (DIABLO) from mitochondria - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-141373] MYS-BID(61-195) [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:141371] Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Translocation of tBID to mitochondria
orthologousEvent	[Reaction:R-GGA-139920] Translocation of tBID to mitochondria - Gallus gallus [Reaction:R-XTR-139920] Translocation of tBID to mitochondria - Xenopus tropicalis [Reaction:R-DRE-139920] Translocation of tBID to mitochondria - Danio rerio [Reaction:R-SSC-139920] Translocation of tBID to mitochondria - Sus scrofa [Reaction:R-BTA-139920] Translocation of tBID to mitochondria - Bos taurus [Reaction:R-CFA-139920] Translocation of tBID to mitochondria - Canis familiaris [Reaction:R-RNO-139920] Translocation of tBID to mitochondria - Rattus norvegicus [Reaction:R-MMU-139920] Translocation of tBID to mitochondria - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-114266] MYS-BID(61-195) [mitochondrial outer membrane]
precedingEvent	[Reaction:R-HSA-141367] Myristoylation of tBID by NMT1 - Homo sapiens
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-139920
summation	[Summation:179267] N-myristoylation targets tBID to the mitochondrial outer mem...
updateTrackers	[UpdateTracker:9787655] Update Tracker - [Reaction:139920] Translocation of tBID to mitochondria - v44:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9787655] Update Tracker - [Reaction:139920] Translocation of tBID to mitochondria - v44:[addLiteratureReference, modifyText]
(replacementInstances)	[Deleted:622301] Deletion of instance: 114267
(precedingEvent)	[Reaction:R-HSA-508162] BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL [Reaction:R-HSA-508163] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 [Reaction:R-HSA-114352] Sequestration of tBID by BCL-2 [Reaction:R-HSA-114284] Release of Cytochrome c from mitochondria [Reaction:R-HSA-168848] tBID binds to inactive BAK protein [Reaction:R-HSA-114307] Release of SMAC (DIABLO) from mitochondria
(hasEvent)	[Pathway:R-HSA-75108] Activation, myristolyation of BID and translocation to mitochondria

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