ERBB4s80:STAT5A complex translocates to the nucleus

Stable Identifier
R-HSA-1254285
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Formation of cytosolic complex of ERBB4s80 and STAT5A promotes translocation of STAT5A to the nucleus, with ERBB4s80 acting as a nuclear chaperone of STAT5A.

Literature References
PubMed ID Title Journal Year
18653779 Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation

Muraoka-Cook, RS, Sandahl, MA, Hunter, D, Miraglia, L, Earp HS, 3rd

Mol Endocrinol 2008
15534001 The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone

Williams, CC, Allison, JG, Vidal, GA, Burow, ME, Beckman, BS, Marrero, L, Jones, FE

J Cell Biol 2004
Participants
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Orthologous Events
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