Reactome | ERBB4s80 binds YAP1

Schema > Reaction > Entries

ERBB4s80 binds YAP1 Show undefined attributes

authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04 [InstanceEdit:9638819] Stern, David F, 2019-02-21
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1254254] Orlic-Milacic, Marija, 2011-04-28
dbId	1254251
displayName	ERBB4s80 binds YAP1
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07 [InstanceEdit:9638824] Orlic-Milacic, Marija, 2019-03-05
eventOf	[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4 - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-1254248] Translocation of ERBB4s80:YAP1 complex to the nucleus - Homo sapiens
input	[DefinedSet:R-HSA-1251980] ERBB4s80 [cytosol] [EntityWithAccessionedSequence:R-HSA-1253345] YAP1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1254250] Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level [LiteratureReference:1254249] WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus [LiteratureReference:1253295] The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	ERBB4s80 binds YAP1
orthologousEvent	[Reaction:R-CEL-1254251] ERBB4s80 binds YAP1 - Caenorhabditis elegans [Reaction:R-GGA-1254251] ERBB4s80 binds YAP1 - Gallus gallus [Reaction:R-XTR-1254251] ERBB4s80 binds YAP1 - Xenopus tropicalis [Reaction:R-DRE-1254251] ERBB4s80 binds YAP1 - Danio rerio [Reaction:R-SSC-1254251] ERBB4s80 binds YAP1 - Sus scrofa [Reaction:R-BTA-1254251] ERBB4s80 binds YAP1 - Bos taurus [Reaction:R-CFA-1254251] ERBB4s80 binds YAP1 - Canis familiaris [Reaction:R-RNO-1254251] ERBB4s80 binds YAP1 - Rattus norvegicus [Reaction:R-MMU-1254251] ERBB4s80 binds YAP1 - Mus musculus
output	[Complex:R-HSA-1253341] ERBB4s80:YAP1 [cytosol]
precedingEvent	[Reaction:R-HSA-1251997] Cleavage of ERBB4m80 by gamma-scretase complex - Homo sapiens
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1979910] Harris, RC, 2011-11-11 [InstanceEdit:1979909] Zeng, F, 2011-11-11 [InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20 [InstanceEdit:2104979] Misior, AM, 2012-02-20
revised	[InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20 [InstanceEdit:2104979] Misior, AM, 2012-02-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1254251
summation	[Summation:1254253] ERBB4s80 interacts with a co-transcriptional activator YAP1 ...

Referrals

(hasEvent)	[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4
(precedingEvent)	[BlackBoxEvent:R-HSA-1254248] Translocation of ERBB4s80:YAP1 complex to the nucleus

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